| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.15.21 |
|---|---|
| Description: | Zeaxanthin epoxidase. |
| Alternative Name: |
Zea-epoxidase. |
| Cath: | 2.40.128.20; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.15.21 |
| BRENDA Enzyme Link: | BRENDA 1.14.15.21 |
| KEGG Enzyme Link: | KEGG1.14.15.21 |
| BioCyc Enzyme Link: | BioCyc 1.14.15.21 |
| ExPASy Enzyme Link: | ExPASy1.14.15.21 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.15.21 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.15.21 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.15.21 |
| IntEnz Enzyme Link: | IntEnz 1.14.15.21 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.15.21 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32443 | all-trans-zeaxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | ([*:1]-[C;H0;+0:2](-[*:3])=[C;H0;+0:4](-[*:5])-[*:6].[*:7]-[C;H0;+0:8](-[*:9])=[C;H0;+0:10](-[*:11])-[*:12]).[*:13]-[Fe;H0;+0:14]-[*:15].[H+;H0:16].[H+;H0:17].[H+;H0:18].[H+;H0:19].[O;H0;+0:20]=[O;H0;+0:21].[O;H0;+0:22]=[O;H0;+0:23]>>([*:1]-[C;H0;+0:2]1(-[*:3])-[O;H0;+0:21]-[C;H0;+0:4]-1(-[*:5])-[*:6].[*:7]-[C;H0;+0:8]1(-[*:9])-[O;H0;+0:20]-[C;H0;+0:10]-1(-[*:11])-[*:12]).[*:13]-[Fe+;H0:14]-[*:15].[OH2;+0:22].[OH2;+0:23] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Xanthophyll cycle enzymes are members of the lipocalin family, the first identified from plants. | Bugos RC, Hieber AD, Yamamoto HY | 1998 Jun 19 | 9624110 |
| FAD is a further essential cofactor of the NAD(P)H and O2-dependent zeaxanthin-epoxidase. | Büch K, Stransky H, Hager A | 1995 Nov 27 | 8521963 |
| Occurrence of the lutein-epoxide cycle in mistletoes of the Loranthaceae and Viscaceae. | Matsubara S, Morosinotto T, Bassi R, Christian AL, Fischer-Schliebs E, Lüttge U, Orthen B, Franco AC, Scarano FR, Förster B, Pogson BJ, Osmond CB | 2003 Oct | 12844265 |
| The de-epoxidase and epoxidase reactions of Mantoniella squamata (Prasinophyceae) exhibit different substrate-specific reaction kinetics compared to spinach. | Frommolt R, Goss R, Wilhelm C | 2001 Jul | 11506368 |
| Plant lipocalins: violaxanthin de-epoxidase and zeaxanthin epoxidase. | Hieber AD, Bugos RC, Yamamoto HY | 2000 Oct 18 | 11058750 |
| Abscisic acid biosynthesis in tomato: regulation of zeaxanthin epoxidase and 9-cis-epoxycarotenoid dioxygenase mRNAs by light/dark cycles, water stress and abscisic acid. | Thompson AJ, Jackson AC, Parker RA, Morpeth DR, Burbidge A, Taylor IB | 2000 Apr | 10890531 |