EC number:1.14.15.26
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.15.26 |
|---|---|
| Description: | Toluene methyl-monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.15.26 |
| BRENDA Enzyme Link: | BRENDA 1.14.15.26 |
| KEGG Enzyme Link: | KEGG1.14.15.26 |
| BioCyc Enzyme Link: | BioCyc 1.14.15.26 |
| ExPASy Enzyme Link: | ExPASy1.14.15.26 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.15.26 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.15.26 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.15.26 |
| IntEnz Enzyme Link: | IntEnz 1.14.15.26 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.15.26 |
EC number:1.14.15.26
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:51592 | 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + toluene = benzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[Fe;H0;+0:4]-[*:5].[*:6]-[Fe;H0;+0:7]-[*:8].[H+;H0:9].[H+;H0:10].[O;H0;+0:11]=[O;H0;+0:12]>>[*:1]-[CH2;+0:2]-[OH;+0:11].[*:3]-[Fe+;H0:4]-[*:5].[*:6]-[Fe+;H0:7]-[*:8].[OH2;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| ntn genes determining the early steps in the divergent catabolism of 4-nitrotoluene and toluene in Pseudomonas sp. strain TW3. | James KD, Williams PA | 1998 Apr | 9555884 |
| Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system. | Suzuki M, Hayakawa T, Shaw JP, Rekik M, Harayama S | 1991 Mar | 1999388 |
| Degradation of chlorotoluenes by in vivo constructed hybrid strains: problems of enzyme specificity, induction and prevention of meta-pathway. | Brinkmann U, Reineke W | 1992 Sep 1 | 1526468 |
| Purification and characterisation of the NADH:acceptor reductase component of xylene monooxygenase encoded by the TOL plasmid pWW0 of Pseudomonas putida mt-2. | Shaw JP, Harayama S | 1992 Oct 1 | 1327782 |
| RHEA:51596 | 2 H(+) + O2 + p-xylene + 2 reduced [2Fe-2S]-[ferredoxin] = 4-methylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[Fe;H0;+0:4]-[*:5].[*:6]-[Fe;H0;+0:7]-[*:8].[H+;H0:9].[H+;H0:10].[O;H0;+0:11]=[O;H0;+0:12]>>[*:1]-[CH2;+0:2]-[OH;+0:11].[*:3]-[Fe+;H0:4]-[*:5].[*:6]-[Fe+;H0:7]-[*:8].[OH2;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| ntn genes determining the early steps in the divergent catabolism of 4-nitrotoluene and toluene in Pseudomonas sp. strain TW3. | James KD, Williams PA | 1998 Apr | 9555884 |
| Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system. | Suzuki M, Hayakawa T, Shaw JP, Rekik M, Harayama S | 1991 Mar | 1999388 |
| Degradation of chlorotoluenes by in vivo constructed hybrid strains: problems of enzyme specificity, induction and prevention of meta-pathway. | Brinkmann U, Reineke W | 1992 Sep 1 | 1526468 |
| Purification and characterisation of the NADH:acceptor reductase component of xylene monooxygenase encoded by the TOL plasmid pWW0 of Pseudomonas putida mt-2. | Shaw JP, Harayama S | 1992 Oct 1 | 1327782 |
| RHEA:51600 | 2 H(+) + m-xylene + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3-methylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[Fe;H0;+0:4]-[*:5].[*:6]-[Fe;H0;+0:7]-[*:8].[H+;H0:9].[H+;H0:10].[O;H0;+0:11]=[O;H0;+0:12]>>[*:1]-[CH2;+0:2]-[OH;+0:11].[*:3]-[Fe+;H0:4]-[*:5].[*:6]-[Fe+;H0:7]-[*:8].[OH2;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| ntn genes determining the early steps in the divergent catabolism of 4-nitrotoluene and toluene in Pseudomonas sp. strain TW3. | James KD, Williams PA | 1998 Apr | 9555884 |
| Primary structure of xylene monooxygenase: similarities to and differences from the alkane hydroxylation system. | Suzuki M, Hayakawa T, Shaw JP, Rekik M, Harayama S | 1991 Mar | 1999388 |
| Degradation of chlorotoluenes by in vivo constructed hybrid strains: problems of enzyme specificity, induction and prevention of meta-pathway. | Brinkmann U, Reineke W | 1992 Sep 1 | 1526468 |
| Purification and characterisation of the NADH:acceptor reductase component of xylene monooxygenase encoded by the TOL plasmid pWW0 of Pseudomonas putida mt-2. | Shaw JP, Harayama S | 1992 Oct 1 | 1327782 |