EC number:1.14.16.3
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.16.3 |
|---|---|
| Description: | Anthranilate 3-monooxygenase. |
| Alternative Name: |
Anthranilic hydroxylase. Anthranilic acid hydroxylase. Anthranilate 3-hydroxylase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.16.3 |
| BRENDA Enzyme Link: | BRENDA 1.14.16.3 |
| KEGG Enzyme Link: | KEGG1.14.16.3 |
| BioCyc Enzyme Link: | BioCyc 1.14.16.3 |
| ExPASy Enzyme Link: | ExPASy1.14.16.3 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.16.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.16.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.16.3 |
| IntEnz Enzyme Link: | IntEnz 1.14.16.3 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.16.3 |
EC number:1.14.16.3
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:21168 | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + anthranilate + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + 3-hydroxyanthranilate + H2O |
| RULE(radius=1) | [*:1]-[c;H0;+0:2]1:[n;H0;+0:3]:[c;H0;+0:4](-[*:5]):[c;H0;+0:6](-[NH;+0:7]-[*:8]):[c;H0;+0:9](=[*:10]):[nH;+0:11]:1.[*:12]:[cH;+0:13]:[*:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]-[C;H0;+0:2]1=[N;H0;+0:11]-[C;H0;+0:9](=[*:10])-[C;H0;+0:6](=[N;H0;+0:7]-[*:8])-[C;H0;+0:4](-[*:5])=[N;H0;+0:3]-1.[*:12]:[c;H0;+0:13](:[*:14])-[OH;+0:15].[OH2;+0:16] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Further studies on tryptophan hydroxylase in rat brainstem and beef pineal. | Jequier E, Robinson DS, Lovenberg W, Sjoerdsma A | 1969 May | 5789774 |