EC number:1.14.16.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.16.5 |
|---|---|
| Description: | Alkylglycerol monooxygenase. |
| Alternative Name: |
Glyceryl-ether monooxygenase. Glyceryl-ether cleaving enzyme. Glyceryl etherase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.16.5 |
| BRENDA Enzyme Link: | BRENDA 1.14.16.5 |
| KEGG Enzyme Link: | KEGG1.14.16.5 |
| BioCyc Enzyme Link: | BioCyc 1.14.16.5 |
| ExPASy Enzyme Link: | ExPASy1.14.16.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.16.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.16.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.16.5 |
| IntEnz Enzyme Link: | IntEnz 1.14.16.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.16.5 |
EC number:1.14.16.5
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:36255 | (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 = (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[CH;+0:5]1-[*:6]-[*:7]-[C;H0;+0:8]2=[N;H0;+0:9]-[C;H0;+0:10](-[*:11])=[N;H0;+0:12]-[C;H0;+0:13](=[*:14])-[CH;+0:15]-2-[NH;+0:16]-1.[O;H0;+0:17]=[O;H0;+0:18]>>[*:4]-[C;H0;+0:5]1=[N;H0;+0:16]-[c;H0;+0:15]2:[c;H0;+0:13](=[*:14]):[n;H0;+0:12]:[c;H0;+0:10](-[*:11]):[nH;+0:9]:[c;H0;+0:8]:2-[*:7]-[*:6]-1.[*:1]-[CH;+0:2](-[*:3])-[OH;+0:17].[OH2;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Glyceryl-ether monooxygenase [EC 1.14.16.5]. A microsomal enzyme of ether lipid metabolism. | Taguchi H, Armarego WL | 1998 Jan | 9436181 |
| Tetrahydropteridine-dependent cleavage enzyme for O-alkyl lipids: substrate specificity. | Snyder F, Malone B, Piantadosi C | 1973 Aug 23 | 4355017 |
| Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes. | Watschinger K, Keller MA, Golderer G, Hermann M, Maglione M, Sarg B, Lindner HH, Hermetter A, Werner-Felmayer G, Konrat R, Hulo N, Werner ER | 2010 Aug 3 | 20643956 |