EC number:1.14.19.2
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.2 | ||
|---|---|---|---|
| Description: | Stearoyl-[acyl-carrier-protein] 9-desaturase. | ||
| Alternative Name: |
Stearyl-ACP desaturase. Stearyl acyl carrier protein desaturase. Acyl-[acyl-carrier-protein] desaturase. | ||
| Prosite: | PDOC00399; | ||
| PDB: |
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| Cath: | 1.10.620.20; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.19.2 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.2 |
| KEGG Enzyme Link: | KEGG1.14.19.2 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.2 |
| ExPASy Enzyme Link: | ExPASy1.14.19.2 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.2 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.2 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.2 |
EC number:1.14.19.2
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:11776 | 2 H(+) + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] = (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[Fe;H0;+0:6]-[*:7].[*:8]-[Fe;H0;+0:9]-[*:10].[H+;H0:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:5]-[Fe+;H0:6]-[*:7].[*:8]-[Fe+;H0:9]-[*:10].[OH2;+0:13].[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position. | Cahoon EB, Lindqvist Y, Schneider G, Shanklin J | 1997 May 13 | 9144157 |
| Fat metabolism in higher plants. Properties of a soluble stearyl-acyl carrier protein desaturase from maturing Carthamus tinctorius. | Jaworski JG, Stumpf PK | 1974 May | 4831331 |
| Enzymatic desaturation of stearyl acyl carrier protein. | Nagai J, Bloch K | 1968 Sep 10 | 4300868 |
| Transcriptional Activation of Two Delta-9 Palmitoyl-ACP Desaturase Genes by MYB115 and MYB118 Is Critical for Biosynthesis of Omega-7 Monounsaturated Fatty Acids in the Endosperm of Arabidopsis Seeds. | Troncoso-Ponce MA, Barthole G, Tremblais G, To A, Miquel M, Lepiniec L, Baud S | 2016 Oct | 27681170 |
| Stearoyl-acyl carrier protein desaturases are associated with floral isolation in sexually deceptive orchids. | Schlüter PM, Xu S, Gagliardini V, Whittle E, Shanklin J, Grossniklaus U, Schiestl FP | 2011 Apr 5 | 21436056 |
| Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs. | Shanklin J, Somerville C | 1991 Mar 15 | 2006187 |
| Heterologous expression of stearoyl-acyl carrier protein desaturase (S-ACP-DES) from Arabidopsis thaliana in Escherichia coli. | Cao Y, Xian M, Yang J, Xu X, Liu W, Li L | 2010 Feb | 19716420 |
| The Arabidopsis stearoyl-acyl carrier protein-desaturase family and the contribution of leaf isoforms to oleic acid synthesis. | Kachroo A, Shanklin J, Whittle E, Lapchyk L, Hildebrand D, Kachroo P | 2007 Jan | 17072561 |