EC number:1.14.19.23
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.23 |
|---|---|
| Description: | Acyl-lipid (n+3)-(Z)-desaturase (ferredoxin). |
| Alternative Name: |
Phosphatidylcholine desaturase. Oleoyl-CoA desaturase. Oleate desaturase. Linoleate synthase. Acyl-lipid omega(6)-desaturase (ferredoxin). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.19.23 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.23 |
| KEGG Enzyme Link: | KEGG1.14.19.23 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.23 |
| ExPASy Enzyme Link: | ExPASy1.14.19.23 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.23 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.23 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.23 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.23 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.23 |
EC number:1.14.19.23
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46376 | a (9Z)-octadecenoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[Fe;H0;+0:6]-[*:7].[*:8]-[Fe;H0;+0:9]-[*:10].[H+;H0:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:5]-[Fe+;H0:6]-[*:7].[*:8]-[Fe+;H0:9]-[*:10].[OH2;+0:13].[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cloning of a higher-plant plastid omega-6 fatty acid desaturase cDNA and its expression in a cyanobacterium. | Hitz WD, Carlson TJ, Booth JR Jr, Kinney AJ, Stecca KL, Yadav NS | 1994 Jun | 8066133 |
| Purification and PCR-based cDNA cloning of a plastidial n-6 desaturase. | Schmidt H, Dresselhaus T, Buck F, Heinz E | 1994 Oct | 7948918 |
| Identification of a gene that complements an Arabidopsis mutant deficient in chloroplast omega 6 desaturase activity. | Falcone DL, Gibson S, Lemieux B, Somerville C | 1994 Dec | 7846158 |
| Involvement of ferredoxin in desaturation of lipid-bound oleate in chloroplasts. | Schmidt H, Heinz E | 1990 Sep | 16667689 |
| Desaturation of oleoyl groups in envelope membranes from spinach chloroplasts. | Schmidt H, Heinz E | 1990 Dec 1 | 11607123 |