| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.40 |
|---|---|
| Description: | Hex-5-enoyl-[acyl-carrier protein] acetylenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.19.40 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.40 |
| KEGG Enzyme Link: | KEGG1.14.19.40 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.40 |
| ExPASy Enzyme Link: | ExPASy1.14.19.40 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.40 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.40 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.40 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.40 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.40 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46572 | 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH3;+0:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:7]-[Fe;H0;+0:8]-[*:9].[H+;H0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[CH;+0:2]=[CH2;+0:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[Fe+;H0:8]-[*:9].[OH2;+0:12].[OH2;+0:13] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| De novo biosynthesis of terminal alkyne-labeled natural products. | Zhu X, Liu J, Zhang W | 2015 Feb | 25531891 |
| RHEA:46568 | 5-hexenoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH2;+0:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:7]-[Fe;H0;+0:8]-[*:9].[H+;H0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[C;H0;+0:2]#[CH;+0:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[Fe+;H0:8]-[*:9].[OH2;+0:12].[OH2;+0:13] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| De novo biosynthesis of terminal alkyne-labeled natural products. | Zhu X, Liu J, Zhang W | 2015 Feb | 25531891 |