Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
ID:1.14.19.40
Description:Hex-5-enoyl-[acyl-carrier protein] acetylenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.19.40
BRENDA Enzyme Link: BRENDA 1.14.19.40
KEGG Enzyme Link: KEGG1.14.19.40
BioCyc Enzyme Link: BioCyc 1.14.19.40
ExPASy Enzyme Link: ExPASy1.14.19.40
EC2PDB Enzyme Link: EC2PDB 1.14.19.40
ExplorEnz Enzyme Link: ExplorEnz 1.14.19.40
PRIAM enzyme-specific profiles Link: PRIAM 1.14.19.40
IntEnz Enzyme Link: IntEnz 1.14.19.40
MEDLINE Enzyme Link: MEDLINE 1.14.19.40
MSA:

1.14.19.40;

Phylogenetic Tree:

1.14.19.40;

Uniprot:
M-CSA:
RHEA:46572 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]
RULE(radius=1) [*:1]-[CH2;+0:2]-[CH3;+0:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:7]-[Fe;H0;+0:8]-[*:9].[H+;H0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[CH;+0:2]=[CH2;+0:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[Fe+;H0:8]-[*:9].[OH2;+0:12].[OH2;+0:13]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
De novo biosynthesis of terminal alkyne-labeled natural products.Zhu X, Liu J, Zhang W2015 Feb25531891

RHEA:46568 5-hexenoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]
RULE(radius=1) [*:1]-[CH;+0:2]=[CH2;+0:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:7]-[Fe;H0;+0:8]-[*:9].[H+;H0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[C;H0;+0:2]#[CH;+0:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[Fe+;H0:8]-[*:9].[OH2;+0:12].[OH2;+0:13]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
De novo biosynthesis of terminal alkyne-labeled natural products.Zhu X, Liu J, Zhang W2015 Feb25531891