EC number:1.14.19.52
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.52 |
|---|---|
| Description: | Camalexin synthase. |
| Alternative Name: |
CYP71B15. Bifunctional dihydrocamalexate synthase/camalexin synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.19.52 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.52 |
| KEGG Enzyme Link: | KEGG1.14.19.52 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.52 |
| ExPASy Enzyme Link: | ExPASy1.14.19.52 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.52 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.52 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.52 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.52 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.52 |
EC number:1.14.19.52
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52776 | 2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = camalexin + CO2 + 2 H(+) + 4 H2O + hydrogen cyanide + 2 oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]#[C;H0;+0:2]-[CH;+0:3](-[S;H0;+0:4]-[CH2;+0:5]-[CH;+0:6](-[NH2;+0:7])-[C;H0;+0:8](=[*:9])-[OH;+0:10])-[c;H0;+0:11](:[*:12]):[*:13].[*:14]-[N;H0;+0:15]1-[*:16]:[*:17]-[NH;+0:18]-[c;H0;+0:19](:[*:20]):[c;H0;+0:21]-1:[nH;+0:22]:[*:23].[*:24]:[nH;+0:25]:[c;H0;+0:26]1:[c;H0;+0:27](:[*:28])-[NH;+0:29]-[*:30]:[*:31]-[N;H0;+0:32]-1-[*:33].[O;H0;+0:34]=[O;H0;+0:35].[O;H0;+0:36]=[O;H0;+0:37]>>[*:1]#[CH;+0:2].[*:14]-[n;H0;+0:15]1:[*:16]:[*:17]:[n;H0;+0:18]:[c;H0;+0:19](:[*:20])-[c;H0;+0:21]:1:[n;H0;+0:22]:[*:23].[*:12]:[c;H0;+0:11](:[*:13])-[c;H0;+0:3]1:[n;H0;+0:7]:[cH;+0:6]:[cH;+0:5]:[s;H0;+0:4]:1.[*:24]:[n;H0;+0:25]:[c;H0;+0:26]1:[n;H0;+0:32](-[*:33]):[*:31]:[*:30]:[n;H0;+0:29]:[c;H0;+0:27]-1:[*:28].[*:9]=[C;H0;+0:8]=[O;H0;+0:10].[OH2;+0:34].[OH2;+0:35].[OH2;+0:36].[OH2;+0:37] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis. | Geu-Flores F, Møldrup ME, Böttcher C, Olsen CE, Scheel D, Halkier BA | 2011 Jun | 21712415 |
| The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana. | Böttcher C, Westphal L, Schmotz C, Prade E, Scheel D, Glawischnig E | 2009 Jun | 19567706 |
| Plant Gene and Alternatively Spliced Variant Annotator. A plant genome annotation pipeline for rice gene and alternatively spliced variant identification with cross-species expressed sequence tag conservation from seven plant species. | Chen FC, Wang SS, Chaw SM, Huang YT, Chuang TJ | 2007 Mar | 17220363 |
| CYP71B15 (PAD3) catalyzes the final step in camalexin biosynthesis. | Schuhegger R, Nafisi M, Mansourova M, Petersen BL, Olsen CE, Svatos A, Halkier BA, Glawischnig E | 2006 Aug | 16766671 |