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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water

ID:	1.14.19.65
Description:	(S)-cheilanthifoline synthase.
Alternative Name:	CYP719A14. (S)-scoulerine oxidase (methylenedioxy-bridge-forming).

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UniProtKB Enzyme Link:	UniProtKB 1.14.19.65
BRENDA Enzyme Link:	BRENDA 1.14.19.65
KEGG Enzyme Link:	KEGG1.14.19.65
BioCyc Enzyme Link:	BioCyc 1.14.19.65
ExPASy Enzyme Link:	ExPASy1.14.19.65
EC2PDB Enzyme Link:	EC2PDB 1.14.19.65
ExplorEnz Enzyme Link:	ExplorEnz 1.14.19.65
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.19.65
IntEnz Enzyme Link:	IntEnz 1.14.19.65
MEDLINE Enzyme Link:	MEDLINE 1.14.19.65

RHEA:20485	(S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-cheilanthifoline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	([:1]-[CH3;+0:2].[:3]-[OH;+0:4]).[:5]-[N;H0;+0:6]1-[CH;+0:7]=[C;H0;+0:8](-[:9])-[CH2;+0:10]-[CH;+0:11]=[CH;+0:12]-1.[H+;H0:13].[O;H0;+0:14]=[O;H0;+0:15]>>[:3]-[O;H0;+0:4]-[CH2;+0:2]-[:1].[:5]-[n+;H0:6]1:[cH;+0:7]:[c;H0;+0:8](-[:9]):[cH;+0:10]:[cH;+0:11]:[cH;+0:12]:1.[OH2;+0:14].[OH2;+0:15]
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Title	Authors	Date	PubMed ID
CYP719A subfamily of cytochrome P450 oxygenases and isoquinoline alkaloid biosynthesis in Eschscholzia californica.	Ikezawa N, Iwasa K, Sato F	2009 Jan	18854999
Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana.	Díaz Chávez ML, Rolf M, Gesell A, Kutchan TM	2011 Mar 1	21094631