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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water

ID:

1.14.19.66

Description:

Berbamunine synthase.

Alternative Name:

(S)-N-methylcoclaurine oxidase (C-O phenol-coupling).

Prosite:

PDOC00081;

PDB:

PDB	Scop

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UniProtKB Enzyme Link:	UniProtKB 1.14.19.66
BRENDA Enzyme Link:	BRENDA 1.14.19.66
KEGG Enzyme Link:	KEGG1.14.19.66
BioCyc Enzyme Link:	BioCyc 1.14.19.66
ExPASy Enzyme Link:	ExPASy1.14.19.66
EC2PDB Enzyme Link:	EC2PDB 1.14.19.66
ExplorEnz Enzyme Link:	ExplorEnz 1.14.19.66
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.19.66
IntEnz Enzyme Link:	IntEnz 1.14.19.66
MEDLINE Enzyme Link:	MEDLINE 1.14.19.66

RHEA:23576	(R)-N-methylcoclaurine + (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase] = berbamunine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	[:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[:9]-[OH;+0:10].[:11]:[cH;+0:12]:[:13].[H+;H0:14].[O;H0;+0:15]=[O;H0;+0:16]>>[:9]-[O;H0;+0:10]-[c;H0;+0:12](:[:11]):[:13].[:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH2;+0:15].[OH2;+0:16]
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Title	Authors	Date	PubMed ID
The purification and characterization of a unique cytochrome P-450 enzyme from Berberis stolonifera plant cell cultures.	Stadler R, Zenk MH	1993 Jan 15	8380416