EC number:1.14.19.71

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
ID:1.14.19.71
Description:Fumitremorgin C synthase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.19.71
BRENDA Enzyme Link: BRENDA 1.14.19.71
KEGG Enzyme Link: KEGG1.14.19.71
BioCyc Enzyme Link: BioCyc 1.14.19.71
ExPASy Enzyme Link: ExPASy1.14.19.71
EC2PDB Enzyme Link: EC2PDB 1.14.19.71
ExplorEnz Enzyme Link: ExplorEnz 1.14.19.71
PRIAM enzyme-specific profiles Link: PRIAM 1.14.19.71
IntEnz Enzyme Link: IntEnz 1.14.19.71
MEDLINE Enzyme Link: MEDLINE 1.14.19.71

EC number:1.14.19.71

MSA:

1.14.19.71;
Phylogenetic Tree:

1.14.19.71;
Uniprot:
M-CSA:
RHEA:35963 O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin A = fumitremorgin C + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[NH;+0:5]-[*:6]).[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[CH2;+0:12]-[CH;+0:13]=[CH;+0:14]-1.[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:4]-[N;H0;+0:5](-[*:6])-[CH;+0:2](-[*:1])-[*:3].[*:7]-[n+;H0:8]1:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:1.[OH2;+0:16].[OH2;+0:17]
Reaction
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References

TitleAuthorsDatePubMed ID
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.Kato N, Suzuki H, Takagi H, Asami Y, Kakeya H, Uramoto M, Usui T, Takahashi S, Sugimoto Y, Osada H2009 Mar 2319226505