| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.73 |
|---|---|
| Description: | (S)-nandinine synthase. |
| Alternative Name: |
CYP719A3. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.19.73 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.73 |
| KEGG Enzyme Link: | KEGG1.14.19.73 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.73 |
| ExPASy Enzyme Link: | ExPASy1.14.19.73 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.73 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.73 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.73 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.73 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.73 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:50364 | (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-nandinine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | ([*:1]-[CH3;+0:2].[*:3]-[OH;+0:4]).[*:5]-[N;H0;+0:6]1-[*:7]:[*:8]-[NH;+0:9]-[c;H0;+0:10](:[*:11]):[c;H0;+0:12]-1:[nH;+0:13]:[*:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:3]-[O;H0;+0:4]-[CH2;+0:2]-[*:1].[*:5]-[n;H0;+0:6]1:[*:7]:[*:8]:[n;H0;+0:9]:[c;H0;+0:10](:[*:11])-[c;H0;+0:12]:1:[n;H0;+0:13]:[*:14].[OH2;+0:15].[OH2;+0:16] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana. | Díaz Chávez ML, Rolf M, Gesell A, Kutchan TM | 2011 Mar 1 | 21094631 |
| Molecular cloning and characterization of methylenedioxy bridge-forming enzymes involved in stylopine biosynthesis in Eschscholzia californica. | Ikezawa N, Iwasa K, Sato F | 2007 Feb | 17250743 |