EC number:1.14.19.8
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water |
| ID: | 1.14.19.8 |
|---|---|
| Description: | Pentalenolactone synthase. |
| Cath: | 1.10.630.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.19.8 |
| BRENDA Enzyme Link: | BRENDA 1.14.19.8 |
| KEGG Enzyme Link: | KEGG1.14.19.8 |
| BioCyc Enzyme Link: | BioCyc 1.14.19.8 |
| ExPASy Enzyme Link: | ExPASy1.14.19.8 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.19.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.19.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.19.8 |
| IntEnz Enzyme Link: | IntEnz 1.14.19.8 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.19.8 |
EC number:1.14.19.8
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:34575 | 2 H(+) + O2 + pentalenolactone F + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalenolactone |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1(-[CH3;+0:3])-[CH2;+0:4]-[*:5]-[*:6]-[CH2;+0:7]-1.[*:8]-[Fe;H0;+0:9]-[*:10].[*:11]-[Fe;H0;+0:12]-[*:13].[H+;H0:14].[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[C;H0;+0:2]1=[CH;+0:4]-[*:5]-[*:6]-[CH;+0:7]-1-[CH3;+0:3].[*:8]-[Fe+;H0:9]-[*:10].[*:11]-[Fe+;H0:12]-[*:13].[OH2;+0:16].[OH2;+0:17] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone. | Zhu D, Seo MJ, Ikeda H, Cane DE | 2011 Feb 23 | 21284395 |