EC number:1.14.99.12
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.99 Miscellaneous |
| ID: | 1.14.99.12 |
|---|---|
| Description: | Androst-4-ene-3,17-dione monooxygenase. |
| Alternative Name: |
Androstenedione monooxygenase. Androstene-3,17-dione hydroxylase. Androst-4-ene-3,17-dione 17-oxidoreductase. 4-androstene-3,17-dione monooxygenase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.99.12 |
| BRENDA Enzyme Link: | BRENDA 1.14.99.12 |
| KEGG Enzyme Link: | KEGG1.14.99.12 |
| BioCyc Enzyme Link: | BioCyc 1.14.99.12 |
| ExPASy Enzyme Link: | ExPASy1.14.99.12 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.99.12 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.99.12 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.99.12 |
| IntEnz Enzyme Link: | IntEnz 1.14.99.12 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.99.12 |
EC number:1.14.99.12
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:22696 | AH2 + androst-4-ene-3,17-dione + O2 = A + H2O + testololactone |
| RULE(radius=1) | [*:1]-[C;H0;+0:2](=[*:3])-[C;H0;+0:4](-[*:5])(-[*:6])-[*:7].[O;H0;+0:8]=[O;H0;+0:9]>>[*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:8]-[C;H0;+0:4](-[*:5])(-[*:6])-[*:7].[OH2;+0:9] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymatic formation of testololactone. | PRAIRIE RL, TALALAY P | 1963 Jan-Feb | 13985909 |