EC number:1.14.99.58
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.99 Miscellaneous |
| ID: | 1.14.99.58 |
|---|---|
| Description: | Heme oxygenase (biliverdin-IX-beta and delta-forming). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.99.58 |
| BRENDA Enzyme Link: | BRENDA 1.14.99.58 |
| KEGG Enzyme Link: | KEGG1.14.99.58 |
| BioCyc Enzyme Link: | BioCyc 1.14.99.58 |
| ExPASy Enzyme Link: | ExPASy1.14.99.58 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.99.58 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.99.58 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.99.58 |
| IntEnz Enzyme Link: | IntEnz 1.14.99.58 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.99.58 |
EC number:1.14.99.58
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52228 | 3 AH2 + 2 H(+) + heme b + 3 O2 = 3 A + biliverdin beta + CO + Fe(2+) + 3 H2O |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural basis for novel delta-regioselective heme oxygenation in the opportunistic pathogen Pseudomonas aeruginosa. | Friedman J, Lad L, Li H, Wilks A, Poulos TL | 2004 May 11 | 15122889 |
| Oxidation of heme to beta- and delta-biliverdin by Pseudomonas aeruginosa heme oxygenase as a consequence of an unusual seating of the heme. | Caignan GA, Deshmukh R, Wilks A, Zeng Y, Huang HW, Moënne-Loccoz P, Bunce RA, Eastman MA, Rivera M | 2002 Dec 18 | 12475329 |
| Homologues of neisserial heme oxygenase in gram-negative bacteria: degradation of heme by the product of the pigA gene of Pseudomonas aeruginosa. | Ratliff M, Zhu W, Deshmukh R, Wilks A, Stojiljkovic I | 2001 Nov | 11591684 |
| RHEA:52224 | 3 AH2 + 3 H(+) + heme b + 3 O2 = 3 A + biliverdin delta + CO + Fe(2+) + 3 H2O |
| RULE(radius=1) | |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural basis for novel delta-regioselective heme oxygenation in the opportunistic pathogen Pseudomonas aeruginosa. | Friedman J, Lad L, Li H, Wilks A, Poulos TL | 2004 May 11 | 15122889 |
| Oxidation of heme to beta- and delta-biliverdin by Pseudomonas aeruginosa heme oxygenase as a consequence of an unusual seating of the heme. | Caignan GA, Deshmukh R, Wilks A, Zeng Y, Huang HW, Moënne-Loccoz P, Bunce RA, Eastman MA, Rivera M | 2002 Dec 18 | 12475329 |
| Homologues of neisserial heme oxygenase in gram-negative bacteria: degradation of heme by the product of the pigA gene of Pseudomonas aeruginosa. | Ratliff M, Zhu W, Deshmukh R, Wilks A, Stojiljkovic I | 2001 Nov | 11591684 |