EC number:1.16.1.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.16 Oxidizing metal ions |
| 1.16.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.16.1.1 | ||
|---|---|---|---|
| Description: | Mercury(II) reductase. | ||
| Alternative Name: |
Mercuric reductase. | ||
| Prosite: | PDOC00073; | ||
| PDB: |
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| Cath: | 3.30.390.30; 3.30.70.100; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.16.1.1 |
| BRENDA Enzyme Link: | BRENDA 1.16.1.1 |
| KEGG Enzyme Link: | KEGG1.16.1.1 |
| BioCyc Enzyme Link: | BioCyc 1.16.1.1 |
| ExPASy Enzyme Link: | ExPASy1.16.1.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.16.1.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.16.1.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.16.1.1 |
| IntEnz Enzyme Link: | IntEnz 1.16.1.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.16.1.1 |
| RHEA:23856 | H(+) + Hg + NADP(+) = Hg(2+) + NADPH |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[H+;H0:9].[Hg;H0;+0:10]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[Hg+2;H0:10] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Mercuric reductase: homology to glutathione reductase and lipoamide dehydrogenase. Iodoacetamide alkylation and sequence of the active site peptide. | Fox BS, Walsh CT | 1983 Aug 16 | 6412751 |
| Mercuric reductase. Purification and characterization of a transposon-encoded flavoprotein containing an oxidation-reduction-active disulfide. | Fox B, Walsh CT | 1982 Mar 10 | 6277900 |
| NmerA of Tn501 mercuric ion reductase: structural modulation of the pKa values of the metal binding cysteine thiols. | Ledwidge R, Hong B, Dötsch V, Miller SM | 2010 Oct 19 | 20828160 |