EC Tree |
1. Oxidoreductases |
1.16 Oxidizing metal ions |
1.16.1 With NAD+ or NADP+ as acceptor |
ID: | 1.16.1.10 |
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Description: | Ferric-chelate reductase (NAD(P)H). |
Alternative Name: |
Ferric reductase. |
Cath: | 2.30.110.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.16.1.10 |
BRENDA Enzyme Link: | BRENDA 1.16.1.10 |
KEGG Enzyme Link: | KEGG1.16.1.10 |
BioCyc Enzyme Link: | BioCyc 1.16.1.10 |
ExPASy Enzyme Link: | ExPASy1.16.1.10 |
EC2PDB Enzyme Link: | EC2PDB 1.16.1.10 |
ExplorEnz Enzyme Link: | ExplorEnz 1.16.1.10 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.16.1.10 |
IntEnz Enzyme Link: | IntEnz 1.16.1.10 |
MEDLINE Enzyme Link: | MEDLINE 1.16.1.10 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:28795 | 2 a Fe(II)-siderophore + H(+) + NADP(+) = 2 a Fe(III)-siderophore + NADPH |
RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[Fe+2;H0:9].[Fe+2;H0:10].[H+;H0:11]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[Fe+3;H0:9].[Fe+3;H0:10] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli. | Wang S, Wu Y, Outten FW | 2011 Jan | 21097627 |
Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase. | Bamford VA, Armour M, Mitchell SA, Cartron M, Andrews SC, Watson KA | 2008 Sep 1 | 18765906 |
RHEA:15061 | 2 a Fe(II)-siderophore + H(+) + NAD(+) = 2 a Fe(III)-siderophore + NADH |
RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[Fe+2;H0:9].[Fe+2;H0:10].[H+;H0:11]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[Fe+3;H0:9].[Fe+3;H0:10] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Isolation and biochemical characterization of two soluble iron(III) reductases from Paracoccus denitrificans. | Mazoch J, Tesarík R, Sedlácek V, Kucera I, Turánek J | 2004 Feb | 14728682 |