EC number:1.16.1.3

Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.16 Oxidizing metal ions
            1.16.1 With NAD+ or NADP+ as acceptor
ID:1.16.1.3
Description:Aquacobalamin reductase.
Alternative Name: Vitamin B(12a) reductase.
NADH:cob(III)alamin oxidoreductase.
NADH-linked aquacobalamin reductase.
B(12a) reductase.
Aquocobalamin reductase.
Cath: 1.20.1200.10; 3.40.50.80; 2.40.30.10; 3.40.50.300;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.16.1.3
BRENDA Enzyme Link: BRENDA 1.16.1.3
KEGG Enzyme Link: KEGG1.16.1.3
BioCyc Enzyme Link: BioCyc 1.16.1.3
ExPASy Enzyme Link: ExPASy1.16.1.3
EC2PDB Enzyme Link: EC2PDB 1.16.1.3
ExplorEnz Enzyme Link: ExplorEnz 1.16.1.3
PRIAM enzyme-specific profiles Link: PRIAM 1.16.1.3
IntEnz Enzyme Link: IntEnz 1.16.1.3
MEDLINE Enzyme Link: MEDLINE 1.16.1.3

EC number:1.16.1.3

MSA:

1.16.1.3;
Phylogenetic Tree:

1.16.1.3;
Uniprot:
M-CSA:
RHEA:24472 2 cob(II)alamin + H(+) + 2 H2O + NAD(+) = 2 aquacob(III)alamin + NADH
RULE(radius=1) [*:1]-[Co-3;H0:2](-[*:3])(-[*:4])(-[*:5])-[*:6].[*:7]-[Co-3;H0:8](-[*:9])(-[*:10])(-[*:11])-[*:12].[*:13]-[c;H0;+0:14]1:[cH;+0:15]:[cH;+0:16]:[cH;+0:17]:[n+;H0:18](-[*:19]):[cH;+0:20]:1.[H+;H0:21].[OH2;+0:22].[OH2;+0:23]>>[*:13]-[C;H0;+0:14]1=[CH;+0:20]-[N;H0;+0:18](-[*:19])-[CH;+0:17]=[CH;+0:16]-[CH2;+0:15]-1.[*:1]-[Co-3;H0:2](-[*:3])(-[*:4])(-[*:5])(-[*:6])-[OH;+0:22].[*:7]-[Co-3;H0:8](-[*:9])(-[*:10])(-[*:11])(-[*:12])-[OH;+0:23]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Enzymatic conversion of vitamin B 12a to adenosyl-B 12: evidence for the existence of two separate reducing systems.Walker GA, Murphy S, Huennekens FM1969 Oct4390543