EC number:1.16.1.5

Enzyme

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     1. Oxidoreductases
        1.16 Oxidizing metal ions
            1.16.1 With NAD+ or NADP+ as acceptor
ID:1.16.1.5
Description:Aquacobalamin reductase (NADPH).
Alternative Name: NADPH:aquacob(III)alamin oxidoreductase.
NADPH-linked aquacobalamin reductase.
reductase.
Aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate)

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.16.1.5
BRENDA Enzyme Link: BRENDA 1.16.1.5
KEGG Enzyme Link: KEGG1.16.1.5
BioCyc Enzyme Link: BioCyc 1.16.1.5
ExPASy Enzyme Link: ExPASy1.16.1.5
EC2PDB Enzyme Link: EC2PDB 1.16.1.5
ExplorEnz Enzyme Link: ExplorEnz 1.16.1.5
PRIAM enzyme-specific profiles Link: PRIAM 1.16.1.5
IntEnz Enzyme Link: IntEnz 1.16.1.5
MEDLINE Enzyme Link: MEDLINE 1.16.1.5

EC number:1.16.1.5

MSA:

1.16.1.5;
Phylogenetic Tree:

1.16.1.5;
Uniprot:
M-CSA:
RHEA:20752 2 cob(II)alamin + H(+) + 2 H2O + NADP(+) = 2 aquacob(III)alamin + NADPH
RULE(radius=1) [*:1]-[Co-3;H0:2](-[*:3])(-[*:4])(-[*:5])-[*:6].[*:7]-[Co-3;H0:8](-[*:9])(-[*:10])(-[*:11])-[*:12].[*:13]-[c;H0;+0:14]1:[cH;+0:15]:[cH;+0:16]:[cH;+0:17]:[n+;H0:18](-[*:19]):[cH;+0:20]:1.[H+;H0:21].[OH2;+0:22].[OH2;+0:23]>>[*:13]-[C;H0;+0:14]1=[CH;+0:20]-[N;H0;+0:18](-[*:19])-[CH;+0:17]=[CH;+0:16]-[CH2;+0:15]-1.[*:1]-[Co-3;H0:2](-[*:3])(-[*:4])(-[*:5])(-[*:6])-[OH;+0:22].[*:7]-[Co-3;H0:8](-[*:9])(-[*:10])(-[*:11])(-[*:12])-[OH;+0:23]
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References

TitleAuthorsDatePubMed ID
Characterization of aquacobalamin reductase (NADPH) from Euglena gracilis.Watanabe F, Yamaji R, Isegawa Y, Yamamoto T, Tamura Y, Nakano Y1993 Sep8373179
Purification and characterization of aquacobalamin reductase (NADPH) from Euglena gracilis.Watanabe F, Oki Y, Nakano Y, Kitaoka S1987 Aug 253114247