EC number:1.17.1.3
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.17 Acting on CH or CH2 groups |
| 1.17.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.17.1.3 |
|---|---|
| Description: | Leucoanthocyanidin reductase. |
| Alternative Name: |
Leucocyanidin reductase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.17.1.3 |
| BRENDA Enzyme Link: | BRENDA 1.17.1.3 |
| KEGG Enzyme Link: | KEGG1.17.1.3 |
| BioCyc Enzyme Link: | BioCyc 1.17.1.3 |
| ExPASy Enzyme Link: | ExPASy1.17.1.3 |
| EC2PDB Enzyme Link: | EC2PDB 1.17.1.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.17.1.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.17.1.3 |
| IntEnz Enzyme Link: | IntEnz 1.17.1.3 |
| MEDLINE Enzyme Link: | MEDLINE 1.17.1.3 |
| RHEA:10616 | (2R,3S)-catechin + H2O + NADP(+) = (2R,3S,4S)-leucocyanidin + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[n+;H0:5]1:[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:1.[OH2;+0:12]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:12].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-[C;H0;+0:9](-[*:10])=[CH;+0:11]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Synthesis of 3,4-cis-[3H]leucocyanidin and enzymatic reduction to catechin. | Tanner GJ, Kristiansen KN | 1993 Mar | 8470799 |
| Crystal structure and catalytic mechanism of leucoanthocyanidin reductase from Vitis vinifera. | Maugé C, Granier T, d'Estaintot BL, Gargouri M, Manigand C, Schmitter JM, Chaudière J, Gallois B | 2010 Apr 9 | 20138891 |
| Proanthocyanidin biosynthesis in plants. Purification of legume leucoanthocyanidin reductase and molecular cloning of its cDNA. | Tanner GJ, Francki KT, Abrahams S, Watson JM, Larkin PJ, Ashton AR | 2003 Aug 22 | 12788945 |