| Title | Authors | Date | PubMed ID |
|---|
| Metabolism of vitamin K and vitamin K 2,3-epoxide via interaction with a common disulfide. | Lee JJ, Fasco MJ | 1984 May 8 | 6733086 |
| Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition. | Whitlon DS, Sadowski JA, Suttie JW | 1978 Apr 18 | 646989 |
| Purification of a vitamin K epoxide reductase that catalyzes conversion of vitamin K 2,3-epoxide to 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone. | Mukharji I, Silverman RB | 1985 May | 3857611 |
| Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration. | Tie JK, Jin DY, Stafford DW | 2014 Mar 28 | 24532791 |
| VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy. | Hammed A, Matagrin B, Spohn G, Prouillac C, Benoit E, Lattard V | 2013 Oct 4 | 23928358 |
| New insights into the catalytic mechanism of vitamin K epoxide reductase (VKORC1) - The catalytic properties of the major mutations of rVKORC1 explain the biological cost associated to mutations. | Matagrin B, Hodroge A, Montagut-Romans A, Andru J, Fourel I, Besse S, Benoit E, Lattard V | 2013 | 23772386 |
| Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay. | Bevans CG, Krettler C, Reinhart C, Tran H, Koßmann K, Watzka M, Oldenburg J | 2013 Aug | 23618698 |
| Human vitamin K epoxide reductase and its bacterial homologue have different membrane topologies and reaction mechanisms. | Tie JK, Jin DY, Stafford DW | 2012 Oct 5 | 22923610 |
| Novel insight into the mechanism of the vitamin K oxidoreductase (VKOR): electron relay through Cys43 and Cys51 reduces VKOR to allow vitamin K reduction and facilitation of vitamin K-dependent protein carboxylation. | Rishavy MA, Usubalieva A, Hallgren KW, Berkner KL | 2011 Mar 4 | 20978134 |
| A quantum chemical study of the mechanism of action of Vitamin K epoxide reductase (VKOR) II. Transition states. | Davis CH, Deerfield D 2nd, Wymore T, Stafford DW, Pedersen LG | 2007 Sep | 17182266 |
| Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle. | Oldenburg J, Bevans CG, Müller CR, Watzka M | 2006 Mar-Apr | 16677080 |
| Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin. | Rost S, Fregin A, Hünerberg M, Bevans CG, Müller CR, Oldenburg J | 2005 Oct | 16270630 |
| The genetic basis of resistance to anticoagulants in rodents. | Pelz HJ, Rost S, Hünerberg M, Fregin A, Heiberg AC, Baert K, MacNicoll AD, Prescott CV, Walker AS, Oldenburg J, Müller CR | 2005 Aug | 15879509 |
| Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system. | Wajih N, Sane DC, Hutson SM, Wallin R | 2005 Mar 18 | 15640149 |
