EC number:1.17.4.5

Enzyme

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EC Tree
     1. Oxidoreductases
        1.17 Acting on CH or CH2 groups
            1.17.4 With a disulfide as acceptor
ID:1.17.4.5
Description:Vitamin-K-epoxide reductase (warfarin-insensitive).
Alternative Name: Vitamin K 2,3-epoxide reductase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.17.4.5
BRENDA Enzyme Link: BRENDA 1.17.4.5
KEGG Enzyme Link: KEGG1.17.4.5
BioCyc Enzyme Link: BioCyc 1.17.4.5
ExPASy Enzyme Link: ExPASy1.17.4.5
EC2PDB Enzyme Link: EC2PDB 1.17.4.5
ExplorEnz Enzyme Link: ExplorEnz 1.17.4.5
PRIAM enzyme-specific profiles Link: PRIAM 1.17.4.5
IntEnz Enzyme Link: IntEnz 1.17.4.5
MEDLINE Enzyme Link: MEDLINE 1.17.4.5

EC number:1.17.4.5

MSA:

1.17.4.5;
Phylogenetic Tree:

1.17.4.5;
Uniprot:
M-CSA:
RHEA:21560 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol = 1,4-dithiothreitol + 2,3-epoxyphylloquinone
RULE(radius=1) [*:1]-[C;H0;+0:2]1(-[*:3])-[*:4]-[O;H0;+0:5]-1.([*:6]-[SH;+0:7].[*:8]-[SH;+0:9])>>[*:1]-[CH;+0:2](-[*:3])-[*:4]-[OH;+0:5].[*:6]-[S;H0;+0:7]-[S;H0;+0:9]-[*:8]
Reaction
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References

TitleAuthorsDatePubMed ID
Purification of a vitamin K epoxide reductase that catalyzes conversion of vitamin K 2,3-epoxide to 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone.Mukharji I, Silverman RB1985 May3857611