EC number:1.17.5.2

Enzyme

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EC Tree
     1. Oxidoreductases
        1.17 Acting on CH or CH2 groups
            1.17.5 With a quinone or similar compound as acceptor
ID:1.17.5.2
Description:Caffeine dehydrogenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.17.5.2
BRENDA Enzyme Link: BRENDA 1.17.5.2
KEGG Enzyme Link: KEGG1.17.5.2
BioCyc Enzyme Link: BioCyc 1.17.5.2
ExPASy Enzyme Link: ExPASy1.17.5.2
EC2PDB Enzyme Link: EC2PDB 1.17.5.2
ExplorEnz Enzyme Link: ExplorEnz 1.17.5.2
PRIAM enzyme-specific profiles Link: PRIAM 1.17.5.2
IntEnz Enzyme Link: IntEnz 1.17.5.2
MEDLINE Enzyme Link: MEDLINE 1.17.5.2

EC number:1.17.5.2

MSA:

1.17.5.2;
Phylogenetic Tree:

1.17.5.2;
Uniprot:
M-CSA:
RHEA:47148 a ubiquinone + caffeine + H2O = 1,3,7-trimethylurate + a ubiquinol
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9](-[*:10])-[C;H0;+0:11]-1=[O;H0;+0:12].[*:13]:[n;H0;+0:14]:[cH;+0:15]:[*:16].[OH2;+0:17]>>[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:7](-[*:8]):[c;H0;+0:9](-[*:10]):[c;H0;+0:11]:1-[OH;+0:12].[*:13]:[nH;+0:14]:[c;H0;+0:15](:[*:16])=[O;H0;+0:17]
Reaction
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References

TitleAuthorsDatePubMed ID
A novel caffeine dehydrogenase in Pseudomonas sp. strain CBB1 oxidizes caffeine to trimethyluric acid.Yu CL, Kale Y, Gopishetty S, Louie TM, Subramanian M2008 Jan17981969
RHEA:27902 caffeine + H2O + ubiquinone-0 = 1,3,7-trimethylurate + ubiquinol-0
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[C;H0;+0:10]-1=[O;H0;+0:11].[*:12]:[n;H0;+0:13]:[cH;+0:14]:[*:15].[OH2;+0:16]>>[*:1]-[c;H0;+0:2]1:[c;H0;+0:10](-[OH;+0:11]):[c;H0;+0:8](-[*:9]):[cH;+0:7]:[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:3]:1-[*:4].[*:12]:[nH;+0:13]:[c;H0;+0:14](:[*:15])=[O;H0;+0:16]
Reaction
Core-to-Core More
Core-to-Core More

References

TitleAuthorsDatePubMed ID
A novel caffeine dehydrogenase in Pseudomonas sp. strain CBB1 oxidizes caffeine to trimethyluric acid.Yu CL, Kale Y, Gopishetty S, Louie TM, Subramanian M2008 Jan17981969