EC number:1.17.7.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.17 Acting on CH or CH2 groups |
| 1.17.7 With an iron-sulfur protein as acceptor |
| ID: | 1.17.7.1 |
|---|---|
| Description: | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin). |
| Alternative Name: |
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase. (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase. |
| Cath: | 3.20.20.20; 3.30.413.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.17.7.1 |
| BRENDA Enzyme Link: | BRENDA 1.17.7.1 |
| KEGG Enzyme Link: | KEGG1.17.7.1 |
| BioCyc Enzyme Link: | BioCyc 1.17.7.1 |
| ExPASy Enzyme Link: | ExPASy1.17.7.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.17.7.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.17.7.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.17.7.1 |
| IntEnz Enzyme Link: | IntEnz 1.17.7.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.17.7.1 |
| RHEA:26119 | (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | ([*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5].[*:6]-[OH;+0:7]).[*:8]-[Fe+;H0:9]-[*:10].[*:11]-[Fe+;H0:12]-[*:13].[OH2;+0:14]>>[*:1]-[CH;+0:2](-[OH;+0:14])-[C;H0;+0:3](-[*:4])(-[*:5])-[O;H0;+0:7]-[*:6].[*:8]-[Fe;H0;+0:9]-[*:10].[*:11]-[Fe;H0;+0:12]-[*:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Isoprenoid biosynthesis in plant chloroplasts via the MEP pathway: direct thylakoid/ferredoxin-dependent photoreduction of GcpE/IspG. | Seemann M, Tse Sum Bui B, Wolff M, Miginiac-Maslow M, Rohmer M | 2006 Mar 6 | 16480720 |
| Cyanobacterial non-mevalonate pathway: (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase interacts with ferredoxin in Thermosynechococcus elongatus BP-1. | Okada K, Hase T | 2005 May 27 | 15792953 |
| Isoprenoid biosynthesis in chloroplasts via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) from Arabidopsis thaliana is a [4Fe-4S] protein. | Seemann M, Wegner P, Schünemann V, Bui BT, Wolff M, Marquet A, Trautwein AX, Rohmer M | 2005 Mar | 15650872 |