EC number:1.17.8.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.17 Acting on CH or CH2 groups |
| 1.17.8 With a flavin as acceptor |
| ID: | 1.17.8.1 |
|---|---|
| Description: | Hydroxysqualene dehydroxylase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.17.8.1 |
| BRENDA Enzyme Link: | BRENDA 1.17.8.1 |
| KEGG Enzyme Link: | KEGG1.17.8.1 |
| BioCyc Enzyme Link: | BioCyc 1.17.8.1 |
| ExPASy Enzyme Link: | ExPASy1.17.8.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.17.8.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.17.8.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.17.8.1 |
| IntEnz Enzyme Link: | IntEnz 1.17.8.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.17.8.1 |
| RHEA:49088 | FAD + H(+) + H2O + squalene = FADH2 + hydroxysqualene |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[n;H0;+0:5]1:[*:6]:[*:7]:[n;H0;+0:8]:[c;H0;+0:9](:[*:10])-[c;H0;+0:11]:1:[n;H0;+0:12]:[*:13].[H+;H0:14].[OH2;+0:15]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:15].[*:4]-[N;H0;+0:5]1-[*:6]:[*:7]-[NH;+0:8]-[c;H0;+0:9](:[*:10]):[c;H0;+0:11]-1:[nH;+0:12]:[*:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes. | Pan JJ, Solbiati JO, Ramamoorthy G, Hillerich BS, Seidel RD, Cronan JE, Almo SC, Poulter CD | 2015 | 26258173 |