Enzyme

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     1. Oxidoreductases
        1.18 Acting on iron-sulfur proteins as donors
            1.18.1 With NAD+ or NADP+ as acceptor
ID:1.18.1.4
Description:Rubredoxin--NAD(P)(+) reductase.
Alternative Name: Rubredoxin-nicotinamide adenine dinucleotide (phosphate) reductase.
Rubredoxin-nicotinamide adenine.
NAD(P)H-rubredoxin oxidoreductase.
NAD(P)-rubredoxin oxidoreductase.
Dinucleotide phosphate reductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.18.1.4
BRENDA Enzyme Link: BRENDA 1.18.1.4
KEGG Enzyme Link: KEGG1.18.1.4
BioCyc Enzyme Link: BioCyc 1.18.1.4
ExPASy Enzyme Link: ExPASy1.18.1.4
EC2PDB Enzyme Link: EC2PDB 1.18.1.4
ExplorEnz Enzyme Link: ExplorEnz 1.18.1.4
PRIAM enzyme-specific profiles Link: PRIAM 1.18.1.4
IntEnz Enzyme Link: IntEnz 1.18.1.4
MEDLINE Enzyme Link: MEDLINE 1.18.1.4
MSA:

1.18.1.4;

Phylogenetic Tree:

1.18.1.4;

Uniprot:
M-CSA:
RHEA:18597 H(+) + NAD(+) + 2 reduced [rubredoxin] = NADH + 2 oxidized [rubredoxin]
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[Fe+2;H0:9].[Fe+2;H0:10].[H+;H0:11]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[Fe+3;H0:9].[Fe+3;H0:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Detection of NAD(P)H--rubredoxin oxidoreductases in Clostridia.Petitdemange H, Blusson H, Gay R1981 Sep 156274224
A hyperactive NAD(P)H:Rubredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus.Ma K, Adams MW1999 Sep10464233

RHEA:13949 H(+) + NADP(+) + 2 reduced [rubredoxin] = NADPH + 2 oxidized [rubredoxin]
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[Fe+2;H0:9].[Fe+2;H0:10].[H+;H0:11]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[Fe+3;H0:9].[Fe+3;H0:10]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Detection of NAD(P)H--rubredoxin oxidoreductases in Clostridia.Petitdemange H, Blusson H, Gay R1981 Sep 156274224
A hyperactive NAD(P)H:Rubredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus.Ma K, Adams MW1999 Sep10464233