EC number:1.18.1.5
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.18 Acting on iron-sulfur proteins as donors |
| 1.18.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.18.1.5 |
|---|---|
| Description: | Putidaredoxin--NAD(+) reductase. |
| Alternative Name: |
Putidaredoxin reductase. |
| Cath: | 3.30.390.30; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.18.1.5 |
| BRENDA Enzyme Link: | BRENDA 1.18.1.5 |
| KEGG Enzyme Link: | KEGG1.18.1.5 |
| BioCyc Enzyme Link: | BioCyc 1.18.1.5 |
| ExPASy Enzyme Link: | ExPASy1.18.1.5 |
| EC2PDB Enzyme Link: | EC2PDB 1.18.1.5 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.18.1.5 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.18.1.5 |
| IntEnz Enzyme Link: | IntEnz 1.18.1.5 |
| MEDLINE Enzyme Link: | MEDLINE 1.18.1.5 |
| RHEA:33063 | H(+) + NAD(+) + 2 reduced [2Fe-2S]-[putidaredoxin] = NADH + 2 oxidized [2Fe-2S]-[putidaredoxin] |
| RULE(radius=1) | [*:1]-[Fe;H0;+0:2]-[*:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:1.[H+;H0:15]>>[*:1]-[Fe+;H0:2]-[*:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[CH;+0:10]-[CH2;+0:11]-[C;H0;+0:12](-[*:13])=[CH;+0:14]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and properties of putidaredoxin reductase. | Roome PW Jr, Philley JC, Peterson JA | 1983 Feb 25 | 6401738 |
| Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida. | Koga H, Yamaguchi E, Matsunaga K, Aramaki H, Horiuchi T | 1989 Nov | 2613690 |
| Putidaredoxin reductase and putidaredoxin. Cloning, sequence determination, and heterologous expression of the proteins. | Peterson JA, Lorence MC, Amarneh B | 1990 Apr 15 | 2180940 |
| Structure of C73G putidaredoxin from Pseudomonas putida. | Smith N, Mayhew M, Holden MJ, Kelly H, Robinson H, Heroux A, Vilker VL, Gallagher DT | 2004 May | 15103126 |
| Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase. | Sevrioukova IF, Li H, Poulos TL | 2004 Feb 27 | 15095867 |
| Crystal structure of putidaredoxin, the [2Fe-2S] component of the P450cam monooxygenase system from Pseudomonas putida. | Sevrioukova IF, Garcia C, Li H, Bhaskar B, Poulos TL | 2003 Oct 17 | 14529624 |
| Putidaredoxin reductase, a new function for an old protein. | Sevrioukova IF, Poulos TL | 2002 Jul 12 | 12011076 |