EC number:1.19.1.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.19 Acting on reduced flavodoxin as donor |
| 1.19.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.19.1.1 |
|---|---|
| Description: | Flavodoxin--NADP(+) reductase. |
| Alternative Name: |
FPR. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.19.1.1 |
| BRENDA Enzyme Link: | BRENDA 1.19.1.1 |
| KEGG Enzyme Link: | KEGG1.19.1.1 |
| BioCyc Enzyme Link: | BioCyc 1.19.1.1 |
| ExPASy Enzyme Link: | ExPASy1.19.1.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.19.1.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.19.1.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.19.1.1 |
| IntEnz Enzyme Link: | IntEnz 1.19.1.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.19.1.1 |
| RHEA:50756 | NADP(+) + reduced [flavodoxin] = 2 H(+) + NADPH + oxidized [flavodoxin] |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]:[nH;+0:10]:[c;H0;+0:11]1:[c;H0;+0:12](:[*:13])-[NH;+0:14]-[*:15]:[*:16]-[N;H0;+0:17]-1-[*:18]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]:[n;H0;+0:10]:[c;H0;+0:11]1:[n;H0;+0:17](-[*:18]):[*:16]:[*:15]:[n;H0;+0:14]:[c;H0;+0:12]-1:[*:13] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterisation of flavodoxin NADP+ oxidoreductase and flavodoxin; key components of electron transfer in Escherichia coli. | McIver L, Leadbeater C, Campopiano DJ, Baxter RL, Daff SN, Chapman SK, Munro AW | 1998 Nov 1 | 9839946 |
| Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of a ferredoxin/flavodoxin-NADP(H) oxidoreductase (Bc0385) from Bacillus cereus. | Skråmo S, Hersleth HP, Hammerstad M, Andersson KK, Røhr ÅK | 2014 Jun | 24915092 |
| The C-terminal extension of bacterial flavodoxin-reductases: involvement in the hydride transfer mechanism from the coenzyme. | Bortolotti A, Sánchez-Azqueta A, Maya CM, Velázquez-Campoy A, Hermoso JA, Medina M, Cortez N | 2014 Jan | 24016470 |
| Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase. | Bortolotti A, Pérez-Dorado I, Goñi G, Medina M, Hermoso JA, Carrillo N, Cortez N | 2009 Feb | 18973834 |
| Electron acceptor specificity of ferredoxin (flavodoxin):NADP+ oxidoreductase from Escherichia coli. | Wan JT, Jarrett JT | 2002 Oct 1 | 12234497 |
| Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase. | Leadbeater C, McIver L, Campopiano DJ, Webster SP, Baxter RL, Kelly SM, Price NC, Lysek DA, Noble MA, Chapman SK, Munro AW | 2000 Dec 1 | 11085917 |