EC number:1.2.1.26
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.2 Acting on the aldehyde or oxo group of donors |
| 1.2.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.2.1.26 |
|---|---|
| Description: | 2,5-dioxovalerate dehydrogenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.2.1.26 |
| BRENDA Enzyme Link: | BRENDA 1.2.1.26 |
| KEGG Enzyme Link: | KEGG1.2.1.26 |
| BioCyc Enzyme Link: | BioCyc 1.2.1.26 |
| ExPASy Enzyme Link: | ExPASy1.2.1.26 |
| EC2PDB Enzyme Link: | EC2PDB 1.2.1.26 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.2.1.26 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.2.1.26 |
| IntEnz Enzyme Link: | IntEnz 1.2.1.26 |
| MEDLINE Enzyme Link: | MEDLINE 1.2.1.26 |
| RHEA:11296 | 2,5-dioxopentanoate + H2O + NADP(+) = 2-oxoglutarate + 2 H(+) + NADPH |
| RULE(radius=1) | [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| D-xylose degradation pathway in the halophilic archaeon Haloferax volcanii. | Johnsen U, Dambeck M, Zaiss H, Fuhrer T, Soppa J, Sauer U, Schönheit P | 2009 Oct 2 | 19584053 |
| New insights into the alternative D-glucarate degradation pathway. | Aghaie A, Lechaplais C, Sirven P, Tricot S, Besnard-Gonnet M, Muselet D, de Berardinis V, Kreimeyer A, Gyapay G, Salanoubat M, Perret A | 2008 Jun 6 | 18364348 |
| A novel alpha-ketoglutaric semialdehyde dehydrogenase: evolutionary insight into an alternative pathway of bacterial L-arabinose metabolism. | Watanabe S, Kodaki T, Makino K | 2006 Sep 29 | 16835232 |