EC number:1.2.1.30
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.2 Acting on the aldehyde or oxo group of donors |
| 1.2.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.2.1.30 |
|---|---|
| Description: | Carboxylate reductase (NADP(+)). |
| Alternative Name: |
Aryl-aldehyde dehydrogenase (NADP(+)). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.2.1.30 |
| BRENDA Enzyme Link: | BRENDA 1.2.1.30 |
| KEGG Enzyme Link: | KEGG1.2.1.30 |
| BioCyc Enzyme Link: | BioCyc 1.2.1.30 |
| ExPASy Enzyme Link: | ExPASy1.2.1.30 |
| EC2PDB Enzyme Link: | EC2PDB 1.2.1.30 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.2.1.30 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.2.1.30 |
| IntEnz Enzyme Link: | IntEnz 1.2.1.30 |
| MEDLINE Enzyme Link: | MEDLINE 1.2.1.30 |
| RHEA:19229 | AMP + an aromatic aldehyde + diphosphate + NADP(+) = an aromatic carboxylate + ATP + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[*:3].[*:4]-[OH;+0:5].[*:6]-[P;H0;+0:7](=[*:8])(-[*:9])-[OH;+0:10].[*:11]-[n+;H0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[c;H0;+0:16](-[*:17]):[cH;+0:18]:1>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:10].[*:11]-[N;H0;+0:12]1-[CH;+0:13]=[CH;+0:14]-[CH2;+0:15]-[C;H0;+0:16](-[*:17])=[CH;+0:18]-1.[*:4]-[O;H0;+0:5]-[P;H0;+0:7](-[*:6])(=[*:8])-[*:9] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification, characterization, and properties of an aryl aldehyde oxidoreductase from Nocardia sp. strain NRRL 5646. | Li T, Rosazza JP | 1997 Jun | 9171390 |
| Reduction of carboxylic acids by Nocardia aldehyde oxidoreductase requires a phosphopantetheinylated enzyme. | Venkitasubramanian P, Daniels L, Rosazza JP | 2007 Jan 5 | 17102130 |