Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.41
Description:Glutamate-5-semialdehyde dehydrogenase.
Alternative Name: Glutamyl-gamma-semialdehyde dehydrogenase.
Gamma-glutamylphosphate reductase.
Beta-glutamylphosphate reductase.
Prosite: PDOC00940;
PDB:
PDBScop
1VLU 8029128; 8041507; 8029128; 8041507;
1O20 8021455; 8033835;
4GHK
2H5G
Cath: 3.40.605.10; 3.40.309.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.41
BRENDA Enzyme Link: BRENDA 1.2.1.41
KEGG Enzyme Link: KEGG1.2.1.41
BioCyc Enzyme Link: BioCyc 1.2.1.41
ExPASy Enzyme Link: ExPASy1.2.1.41
EC2PDB Enzyme Link: EC2PDB 1.2.1.41
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.41
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.41
IntEnz Enzyme Link: IntEnz 1.2.1.41
MEDLINE Enzyme Link: MEDLINE 1.2.1.41
MSA:

1.2.1.41;

Phylogenetic Tree:

1.2.1.41;

Uniprot:
M-CSA:
RHEA:19541 L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[n+;H0:4]1:[cH;+0:5]:[cH;+0:6]:[cH;+0:7]:[c;H0;+0:8](-[*:9]):[cH;+0:10]:1.[*:11]=[CH;+0:12]-[*:13]>>[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[CH;+0:6]-[CH2;+0:7]-[C;H0;+0:8](-[*:9])=[CH;+0:10]-1.[*:11]=[C;H0;+0:12](-[*:13])-[O;H0;+0:2]-[*:1]
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