EC number:1.2.1.44
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.2 Acting on the aldehyde or oxo group of donors |
| 1.2.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.2.1.44 |
|---|---|
| Description: | Cinnamoyl-CoA reductase. |
| Cath: | 3.40.50.720; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.2.1.44 |
| BRENDA Enzyme Link: | BRENDA 1.2.1.44 |
| KEGG Enzyme Link: | KEGG1.2.1.44 |
| BioCyc Enzyme Link: | BioCyc 1.2.1.44 |
| ExPASy Enzyme Link: | ExPASy1.2.1.44 |
| EC2PDB Enzyme Link: | EC2PDB 1.2.1.44 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.2.1.44 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.2.1.44 |
| IntEnz Enzyme Link: | IntEnz 1.2.1.44 |
| MEDLINE Enzyme Link: | MEDLINE 1.2.1.44 |
| RHEA:10620 | (E)-cinnamaldehyde + CoA + NADP(+) = (E)-cinnamoyl-CoA + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[SH;+0:2].[*:3]-[c;H0;+0:4]1:[cH;+0:5]:[cH;+0:6]:[cH;+0:7]:[n+;H0:8](-[*:9]):[cH;+0:10]:1.[*:11]=[CH;+0:12]-[*:13]>>[*:3]-[C;H0;+0:4]1=[CH;+0:10]-[N;H0;+0:8](-[*:9])-[CH;+0:7]=[CH;+0:6]-[CH2;+0:5]-1.[*:1]-[S;H0;+0:2]-[C;H0;+0:12](=[*:11])-[*:13] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax). | Wengenmayer H, Ebel J, Grisebach H | 1976 Jun 1 | 7454 |
| Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana). | Sarni F, Grand C, Boudet AM | 1984 Mar 1 | 6365550 |
| Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis. | Pan H, Zhou R, Louie GV, Mühlemann JK, Bomati EK, Bowman ME, Dudareva N, Dixon RA, Noel JP, Wang X | 2014 Sep | 25217505 |
| Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia. | Gross GG, Kreiten W | 1975 Jun 15 | 236926 |
| Two cinnamoyl-CoA reductase (CCR) genes from Arabidopsis thaliana are differentially expressed during development and in response to infection with pathogenic bacteria. | Lauvergeat V, Lacomme C, Lacombe E, Lasserre E, Roby D, Grima-Pettenati J | 2001 Aug | 11430991 |