EC number:1.2.1.46

Enzyme

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EC Tree
     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.46
Description:Formaldehyde dehydrogenase.
Prosite: PDOC00058;
PDB:
PDBScop
Cath: 3.40.50.720; 3.90.180.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.46
BRENDA Enzyme Link: BRENDA 1.2.1.46
KEGG Enzyme Link: KEGG1.2.1.46
BioCyc Enzyme Link: BioCyc 1.2.1.46
ExPASy Enzyme Link: ExPASy1.2.1.46
EC2PDB Enzyme Link: EC2PDB 1.2.1.46
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.46
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.46
IntEnz Enzyme Link: IntEnz 1.2.1.46
MEDLINE Enzyme Link: MEDLINE 1.2.1.46

EC number:1.2.1.46

MSA:

1.2.1.46;
Phylogenetic Tree:

1.2.1.46;
Uniprot:
M-CSA:
RHEA:16425 formaldehyde + H2O + NAD(+) = formate + 2 H(+) + NADH
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH2;+0:10].[OH2;+0:11]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[CH;+0:10]-[OH;+0:11]
Reaction
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References

TitleAuthorsDatePubMed ID
P. putida formaldehyde dehydrogenase. An alcohol dehydrogenase masquerading as an aldehyde dehydrogenase.Oppenheimer NJ, Henehan GT, Huete-Pérez JA, Ito K19979059646
Enzymological aspects of caffeine demethylation and formaldehyde oxidation by Pseudomonas putida C1.Hohnloser W, Osswald B, Lingens F1980 Dec7461603
Formaldehyde dehydrogenase from Pseudomonas putida: a zinc metalloenzyme.Ogushi S, Ando M, Tsuru D1984 Nov6526822