EC number:1.2.1.52

Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.52
Description:Oxoglutarate dehydrogenase (NADP(+)).

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.52
BRENDA Enzyme Link: BRENDA 1.2.1.52
KEGG Enzyme Link: KEGG1.2.1.52
BioCyc Enzyme Link: BioCyc 1.2.1.52
ExPASy Enzyme Link: ExPASy1.2.1.52
EC2PDB Enzyme Link: EC2PDB 1.2.1.52
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.52
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.52
IntEnz Enzyme Link: IntEnz 1.2.1.52
MEDLINE Enzyme Link: MEDLINE 1.2.1.52

EC number:1.2.1.52

MSA:

1.2.1.52;
Phylogenetic Tree:

1.2.1.52;
Uniprot:
M-CSA:
RHEA:21400 2-oxoglutarate + CoA + NADP(+) = CO2 + NADPH + succinyl-CoA
RULE(radius=1) [*:1]-[SH;+0:2].[*:3]-[c;H0;+0:4]1:[cH;+0:5]:[cH;+0:6]:[cH;+0:7]:[n+;H0:8](-[*:9]):[cH;+0:10]:1.[*:11]=[C;H0;+0:12](-[*:13])-[C;H0;+0:14](=[*:15])-[OH;+0:16]>>[*:3]-[C;H0;+0:4]1=[CH;+0:10]-[N;H0;+0:8](-[*:9])-[CH;+0:7]=[CH;+0:6]-[CH2;+0:5]-1.[*:11]=[C;H0;+0:12](-[*:13])-[S;H0;+0:2]-[*:1].[*:15]=[C;H0;+0:14]=[O;H0;+0:16]
Reaction
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References

TitleAuthorsDatePubMed ID
Occurrence of oxygen-sensitive, NADP+-dependent pyruvate dehydrogenase in mitochondria of Euglena gracilis.Inui H, Miyatake K, Nakano Y, Kitaoka S1984 Sep6438078