EC number:1.2.1.69

Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.69
Description:Fluoroacetaldehyde dehydrogenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.69
BRENDA Enzyme Link: BRENDA 1.2.1.69
KEGG Enzyme Link: KEGG1.2.1.69
BioCyc Enzyme Link: BioCyc 1.2.1.69
ExPASy Enzyme Link: ExPASy1.2.1.69
EC2PDB Enzyme Link: EC2PDB 1.2.1.69
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.69
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.69
IntEnz Enzyme Link: IntEnz 1.2.1.69
MEDLINE Enzyme Link: MEDLINE 1.2.1.69

EC number:1.2.1.69

MSA:

1.2.1.69;
Phylogenetic Tree:

1.2.1.69;
Uniprot:
M-CSA:
RHEA:16677 fluoroacetaldehyde + H2O + NAD(+) = fluoroacetate + 2 H(+) + NADH
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]
Reaction
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References

TitleAuthorsDatePubMed ID
Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya.Murphy CD, Moss SJ, O'Hagan D2001 Oct11571203
Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya.Murphy CD, Schaffrath C, O'Hagan D2003 Jul12738270