EC number:1.2.1.70
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.2 Acting on the aldehyde or oxo group of donors |
| 1.2.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.2.1.70 |
|---|---|
| Description: | Glutamyl-tRNA reductase. |
| Prosite: | PDOC00608; |
| PDB: | |
| Cath: | 1.10.1200.70; 3.30.460.30; 3.40.50.720; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.2.1.70 |
| BRENDA Enzyme Link: | BRENDA 1.2.1.70 |
| KEGG Enzyme Link: | KEGG1.2.1.70 |
| BioCyc Enzyme Link: | BioCyc 1.2.1.70 |
| ExPASy Enzyme Link: | ExPASy1.2.1.70 |
| EC2PDB Enzyme Link: | EC2PDB 1.2.1.70 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.2.1.70 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.2.1.70 |
| IntEnz Enzyme Link: | IntEnz 1.2.1.70 |
| MEDLINE Enzyme Link: | MEDLINE 1.2.1.70 |
| RHEA:12344 | (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[n+;H0:4]1:[cH;+0:5]:[cH;+0:6]:[cH;+0:7]:[c;H0;+0:8](-[*:9]):[cH;+0:10]:1.[*:11]=[CH;+0:12]-[*:13]>>[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[CH;+0:6]-[CH2;+0:7]-[C;H0;+0:8](-[*:9])=[CH;+0:10]-1.[*:1]-[O;H0;+0:2]-[C;H0;+0:12](=[*:11])-[*:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The hemA gene encoding glutamyl-tRNA reductase from the archaeon Methanobacterium thermoautotrophicum strain Marburg. | Hungerer C, Weiss DS, Thauer RK, Jahn D | 1996 Jul | 8831980 |
| Purification and partial characterisation of barley glutamyl-tRNA(Glu) reductase, the enzyme that directs glutamate to chlorophyll biosynthesis. | Pontoppidan B, Kannangara CG | 1994 Oct 15 | 7957167 |
| Light regulation of chlorophyll biosynthesis at the level of 5-aminolevulinate formation in Arabidopsis. | Ilag LL, Kumar AM, Söll D | 1994 Feb | 7908550 |
| Escherichia coli glutamyl-tRNA reductase. Trapping the thioester intermediate. | Schauer S, Chaturvedi S, Randau L, Moser J, Kitabatake M, Lorenz S, Verkamp E, Schubert WD, Nakayashiki T, Murai M, Wall K, Thomann HU, Heinz DW, Inokuchi H, Söll D, Jahn D | 2002 Dec 13 | 12370189 |
| Chlorophyll Biosynthesis. | Von Wettstein D, Gough S, Kannangara CG | 1995 Jul | 12242396 |