EC number:1.2.1.72

Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.72
Description:Erythrose-4-phosphate dehydrogenase.
Alternative Name: Erythrose 4-phosphate dehydrogenase.
E4PDH.
E4P dehydrogenase.
Prosite: PDOC00069;
PDB:
PDBScop
Cath: 3.20.20.70; 3.30.360.10; 3.40.50.720; 3.40.50.880; 3.40.640.10; 3.90.1150.10; 2.30.110.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.72
BRENDA Enzyme Link: BRENDA 1.2.1.72
KEGG Enzyme Link: KEGG1.2.1.72
BioCyc Enzyme Link: BioCyc 1.2.1.72
ExPASy Enzyme Link: ExPASy1.2.1.72
EC2PDB Enzyme Link: EC2PDB 1.2.1.72
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.72
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.72
IntEnz Enzyme Link: IntEnz 1.2.1.72
MEDLINE Enzyme Link: MEDLINE 1.2.1.72

EC number:1.2.1.72

MSA:

1.2.1.72;
Phylogenetic Tree:

1.2.1.72;
Uniprot:
M-CSA:
RHEA:12056 D-erythrose 4-phosphate + H2O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]
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References

TitleAuthorsDatePubMed ID
Involvement of the gapA- and epd (gapB)-encoded dehydrogenases in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12.Yang Y, Zhao G, Man TK, Winkler ME1998 Aug9696782
Comparative enzymatic properties of GapB-encoded erythrose-4-phosphate dehydrogenase of Escherichia coli and phosphorylating glyceraldehyde-3-phosphate dehydrogenase.Boschi-Muller S, Azza S, Pollastro D, Corbier C, Branlant G1997 Jun 139182530
Biochemical characterization of gapB-encoded erythrose 4-phosphate dehydrogenase of Escherichia coli K-12 and its possible role in pyridoxal 5'-phosphate biosynthesis.Zhao G, Pease AJ, Bharani N, Winkler ME1995 May7751290