EC number:1.2.1.77

Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.77
Description:3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP(+)).
Alternative Name: 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase.
Prosite: PDOC00068;
PDB:
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3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.77
BRENDA Enzyme Link: BRENDA 1.2.1.77
KEGG Enzyme Link: KEGG1.2.1.77
BioCyc Enzyme Link: BioCyc 1.2.1.77
ExPASy Enzyme Link: ExPASy1.2.1.77
EC2PDB Enzyme Link: EC2PDB 1.2.1.77
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.77
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.77
IntEnz Enzyme Link: IntEnz 1.2.1.77
MEDLINE Enzyme Link: MEDLINE 1.2.1.77

EC number:1.2.1.77

MSA:

1.2.1.77;
Phylogenetic Tree:

1.2.1.77;
Uniprot:
M-CSA:
RHEA:25391 (3Z)-6-oxohex-3-enoyl-CoA + H2O + NADP(+) = cis-3,4-dehydroadipyl-CoA + 2 H(+) + NADPH
RULE(radius=1) [*:1]-[c;H0;+0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[n+;H0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[C;H0;+0:2]1=[CH;+0:8]-[N;H0;+0:6](-[*:7])-[CH;+0:5]=[CH;+0:4]-[CH2;+0:3]-1.[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]
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References

TitleAuthorsDatePubMed ID
Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400.Bains J, Boulanger MJ2008 Jun 618462753
Aerobic benzoyl-coenzyme A (CoA) catabolic pathway in Azoarcus evansii: conversion of ring cleavage product by 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase.Gescher J, Ismail W, Olgeschläger E, Eisenreich W, Wörth J, Fuchs G2006 Apr16585753