EC number:1.2.1.85

Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.85
Description:2-hydroxymuconate-6-semialdehyde dehydrogenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.85
BRENDA Enzyme Link: BRENDA 1.2.1.85
KEGG Enzyme Link: KEGG1.2.1.85
BioCyc Enzyme Link: BioCyc 1.2.1.85
ExPASy Enzyme Link: ExPASy1.2.1.85
EC2PDB Enzyme Link: EC2PDB 1.2.1.85
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.85
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.85
IntEnz Enzyme Link: IntEnz 1.2.1.85
MEDLINE Enzyme Link: MEDLINE 1.2.1.85

EC number:1.2.1.85

MSA:

1.2.1.85;
Phylogenetic Tree:

1.2.1.85;
Uniprot:
M-CSA:
RHEA:34219 (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O + NAD(+) = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+) + NADH
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]
Reaction
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References

TitleAuthorsDatePubMed ID
Uncovering the protocatechuate 2,3-cleavage pathway genes.Kasai D, Fujinami T, Abe T, Mase K, Katayama Y, Fukuda M, Masai E2009 Nov19717587
Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of Pseudomonas putida.Inoue J, Shaw JP, Rekik M, Harayama S1995 Mar7868591
Metabolism of 4-amino-3-hydroxybenzoic acid by Bordetella sp. strain 10d: A different modified meta-cleavage pathway for 2-aminophenols.Orii C, Takenaka S, Murakami S, Aoki K2006 Nov17090920