EC number:1.2.1.89

Enzyme

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     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.89
Description:D-glyceraldehyde dehydrogenase (NADP(+)).
Alternative Name: Glyceraldehyde dehydrogenase.
GADH.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.89
BRENDA Enzyme Link: BRENDA 1.2.1.89
KEGG Enzyme Link: KEGG1.2.1.89
BioCyc Enzyme Link: BioCyc 1.2.1.89
ExPASy Enzyme Link: ExPASy1.2.1.89
EC2PDB Enzyme Link: EC2PDB 1.2.1.89
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.89
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.89
IntEnz Enzyme Link: IntEnz 1.2.1.89
MEDLINE Enzyme Link: MEDLINE 1.2.1.89

EC number:1.2.1.89

MSA:

1.2.1.89;
Phylogenetic Tree:

1.2.1.89;
Uniprot:
M-CSA:
RHEA:40163 D-glyceraldehyde + H2O + NADP(+) = D-glycerate + 2 H(+) + NADPH
RULE(radius=1) [*:1]-[n+;H0:2]1:[cH;+0:3]:[cH;+0:4]:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:1.[*:9]=[CH;+0:10]-[*:11].[OH2;+0:12]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[CH;+0:4]-[CH2;+0:5]-[C;H0;+0:6](-[*:7])=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[OH;+0:12]
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References

TitleAuthorsDatePubMed ID
Identification and characterization of Thermoplasma acidophilum glyceraldehyde dehydrogenase: a new class of NADP+-specific aldehyde dehydrogenase.Jung JH, Lee SB2006 Jul 116566751
Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily.Reher M, Schönheit P2006 Feb 2016458304