EC number:1.2.1.95

Enzyme

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EC Tree
     1. Oxidoreductases
        1.2 Acting on the aldehyde or oxo group of donors
            1.2.1 With NAD+ or NADP+ as acceptor
ID:1.2.1.95
Description:L-2-aminoadipate reductase.
Alternative Name: Alpha-aminoadipate reductase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.2.1.95
BRENDA Enzyme Link: BRENDA 1.2.1.95
KEGG Enzyme Link: KEGG1.2.1.95
BioCyc Enzyme Link: BioCyc 1.2.1.95
ExPASy Enzyme Link: ExPASy1.2.1.95
EC2PDB Enzyme Link: EC2PDB 1.2.1.95
ExplorEnz Enzyme Link: ExplorEnz 1.2.1.95
PRIAM enzyme-specific profiles Link: PRIAM 1.2.1.95
IntEnz Enzyme Link: IntEnz 1.2.1.95
MEDLINE Enzyme Link: MEDLINE 1.2.1.95

EC number:1.2.1.95

MSA:

1.2.1.95;
Phylogenetic Tree:

1.2.1.95;
Uniprot:
M-CSA:
RHEA:46936 (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) = ATP + H(+) + L-2-aminoadipate + NADPH
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[P;H0;+0:4](=[*:5])(-[*:6])-[OH;+0:7].[*:8]-[n+;H0:9]1:[cH;+0:10]:[cH;+0:11]:[cH;+0:12]:[c;H0;+0:13](-[*:14]):[cH;+0:15]:1.[*:16]=[CH;+0:17]-[*:18]>>[*:8]-[N;H0;+0:9]1-[CH;+0:10]=[CH;+0:11]-[CH2;+0:12]-[C;H0;+0:13](-[*:14])=[CH;+0:15]-1.[*:1]-[O;H0;+0:2]-[P;H0;+0:4](-[*:3])(=[*:5])-[*:6].[*:16]=[C;H0;+0:17](-[*:18])-[OH;+0:7]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5.Ehmann DE, Gehring AM, Walsh CT1999 May 1110320345