EC number:1.2.7.8
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.2 Acting on the aldehyde or oxo group of donors |
| 1.2.7 With an iron-sulfur protein as acceptor |
| ID: | 1.2.7.8 |
|---|---|
| Description: | Indolepyruvate ferredoxin oxidoreductase. |
| Alternative Name: |
IOR. 3-(indol-3-yl)pyruvate synthase (ferredoxin). |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.2.7.8 |
| BRENDA Enzyme Link: | BRENDA 1.2.7.8 |
| KEGG Enzyme Link: | KEGG1.2.7.8 |
| BioCyc Enzyme Link: | BioCyc 1.2.7.8 |
| ExPASy Enzyme Link: | ExPASy1.2.7.8 |
| EC2PDB Enzyme Link: | EC2PDB 1.2.7.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.2.7.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.2.7.8 |
| IntEnz Enzyme Link: | IntEnz 1.2.7.8 |
| MEDLINE Enzyme Link: | MEDLINE 1.2.7.8 |
| RHEA:12645 | CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + S-2-(indol-3-yl)acetyl-CoA |
| RULE(radius=1) | [*:1]-[Fe+;H0:2]-[*:3].[*:4]-[Fe+;H0:5]-[*:6].[*:7]-[SH;+0:8].[*:9]=[C;H0;+0:10](-[OH;+0:11])-[C;H0;+0:12](=[*:13])-[*:14]>>[*:1]-[Fe;H0;+0:2]-[*:3].[*:4]-[Fe;H0;+0:5]-[*:6].[*:13]=[C;H0;+0:12](-[*:14])-[S;H0;+0:8]-[*:7].[*:9]=[C;H0;+0:10]=[O;H0;+0:11] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Indolepyruvate ferredoxin oxidoreductase from Pyrococcus sp. KOD1 possesses a mosaic structure showing features of various oxidoreductases. | Siddiqui MA, Fujiwara S, Imanaka T | 1997 Apr 28 | 9180697 |
| Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum. | Tersteegen A, Linder D, Thauer RK, Hedderich R | 1997 Mar 15 | 9108258 |
| Indolepyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus. A new enzyme involved in peptide fermentation. | Mai X, Adams MW | 1994 Jun 17 | 8206994 |
| 2-keto acid oxidoreductases from Pyrococcus furiosus and Thermococcus litoralis. | Schut GJ, Menon AL, Adams MW | 2001 | 11265457 |