EC number:1.23.1.1
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.23 Reducing C-O-C group as acceptor |
| 1.23.1 With NADH or NADPH as donor |
| ID: | 1.23.1.1 |
|---|---|
| Description: | (+)-pinoresinol reductase. |
| Alternative Name: |
Pinoresinol/lariciresinol reductase. Pinoresinol-lariciresinol reductases. (+)-pinoresinol/(+)-lariciresinol. (+)-pinoresinol-(+)-lariciresinol reductase. |
| Cath: | 3.40.50.720; 3.90.25.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.23.1.1 |
| BRENDA Enzyme Link: | BRENDA 1.23.1.1 |
| KEGG Enzyme Link: | KEGG1.23.1.1 |
| BioCyc Enzyme Link: | BioCyc 1.23.1.1 |
| ExPASy Enzyme Link: | ExPASy1.23.1.1 |
| EC2PDB Enzyme Link: | EC2PDB 1.23.1.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.23.1.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.23.1.1 |
| IntEnz Enzyme Link: | IntEnz 1.23.1.1 |
| MEDLINE Enzyme Link: | MEDLINE 1.23.1.1 |
| RHEA:34419 | (+)-lariciresinol + NADP(+) = (+)-pinoresinol + H(+) + NADPH |
| RULE(radius=1) | ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| (+)-Pinoresinol/(+)-lariciresinol reductase from Forsythia intermedia. Protein purification, cDNA cloning, heterologous expression and comparison to isoflavone reductase. | Dinkova-Kostova AT, Gang DR, Davin LB, Bedgar DL, Chu A, Lewis NG | 1996 Nov 15 | 8910615 |
| Stereospecificity of (+)-pinoresinol and (+)-lariciresinol reductases from Forsythia intermedia. | Chu A, Dinkova A, Davin LB, Bedgar DL, Lewis NG | 1993 Dec 25 | 8262939 |
| Hinokinin biosynthesis in Linum corymbulosum Reichenb. | Bayindir U, Alfermann AW, Fuss E | 2008 Sep | 18489708 |
| (+)-Pinoresinol/(-)-lariciresinol reductase from Linum perenne Himmelszelt involved in the biosynthesis of justicidin B. | Hemmati S, Schmidt TJ, Fuss E | 2007 Feb 20 | 17257599 |