EC number:1.23.1.2

Enzyme

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     1. Oxidoreductases
        1.23 Reducing C-O-C group as acceptor
            1.23.1 With NADH or NADPH as donor
ID:1.23.1.2
Description:(+)-lariciresinol reductase.
Alternative Name: Pinoresinol/lariciresinol reductase.
Pinoresinol-lariciresinol reductases.
(+)-pinoresinol/(+)-lariciresinol.
(+)-pinoresinol-(+)-lariciresinol reductase.
Cath: 3.40.50.720; 3.90.25.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.23.1.2
BRENDA Enzyme Link: BRENDA 1.23.1.2
KEGG Enzyme Link: KEGG1.23.1.2
BioCyc Enzyme Link: BioCyc 1.23.1.2
ExPASy Enzyme Link: ExPASy1.23.1.2
EC2PDB Enzyme Link: EC2PDB 1.23.1.2
ExplorEnz Enzyme Link: ExplorEnz 1.23.1.2
PRIAM enzyme-specific profiles Link: PRIAM 1.23.1.2
IntEnz Enzyme Link: IntEnz 1.23.1.2
MEDLINE Enzyme Link: MEDLINE 1.23.1.2

EC number:1.23.1.2

MSA:

1.23.1.2;
Phylogenetic Tree:

1.23.1.2;
Uniprot:
M-CSA:
RHEA:34423 (-)-secoisolariciresinol + NADP(+) = (+)-lariciresinol + H(+) + NADPH
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1.[*:4]-[O;H0;+0:5]-[CH;+0:2](-[*:1])-[*:3]
Reaction
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References

TitleAuthorsDatePubMed ID
Stereospecificity of (+)-pinoresinol and (+)-lariciresinol reductases from Forsythia intermedia.Chu A, Dinkova A, Davin LB, Bedgar DL, Lewis NG1993 Dec 258262939