Enzyme

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EC Tree
     1. Oxidoreductases
        1.23 Reducing C-O-C group as acceptor
            1.23.1 With NADH or NADPH as donor
ID:1.23.1.3
Description:(-)-pinoresinol reductase.
Alternative Name: Pinoresinol/lariciresinol reductase.
Pinoresinol-lariciresinol reductases.
(-)-pinoresinol-(-)-lariciresinol reductase.
Cath: 3.40.50.720; 3.90.25.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.23.1.3
BRENDA Enzyme Link: BRENDA 1.23.1.3
KEGG Enzyme Link: KEGG1.23.1.3
BioCyc Enzyme Link: BioCyc 1.23.1.3
ExPASy Enzyme Link: ExPASy1.23.1.3
EC2PDB Enzyme Link: EC2PDB 1.23.1.3
ExplorEnz Enzyme Link: ExplorEnz 1.23.1.3
PRIAM enzyme-specific profiles Link: PRIAM 1.23.1.3
IntEnz Enzyme Link: IntEnz 1.23.1.3
MEDLINE Enzyme Link: MEDLINE 1.23.1.3
MSA:

1.23.1.3;

Phylogenetic Tree:

1.23.1.3;

Uniprot:
M-CSA:
RHEA:34427 (-)-lariciresinol + NADP(+) = (-)-pinoresinol + H(+) + NADPH
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]-[OH;+0:5]).[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:5]-[*:4].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Recombinant pinoresinol-lariciresinol reductases from western red cedar (Thuja plicata) catalyze opposite enantiospecific conversions.Fujita M, Gang DR, Davin LB, Lewis NG1999 Jan 89872995
(+)-Pinoresinol/(-)-lariciresinol reductase from Linum perenne Himmelszelt involved in the biosynthesis of justicidin B.Hemmati S, Schmidt TJ, Fuss E2007 Feb 2017257599