EC number:1.3.1.100
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.100 |
|---|---|
| Description: | Chanoclavine-I aldehyde reductase. |
| Cath: | 3.20.20.70; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.100 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.100 |
| KEGG Enzyme Link: | KEGG1.3.1.100 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.100 |
| ExPASy Enzyme Link: | ExPASy1.3.1.100 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.100 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.100 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.100 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.100 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.100 |
EC number:1.3.1.100
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:35947 | dihydrochanoclavine-I aldehyde + NADP(+) = chanoclavine-I aldehyde + H(+) + NADPH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[CH2;+0:4]-[*:5].[*:6]-[n+;H0:7]1:[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:[c;H0;+0:11](-[*:12]):[cH;+0:13]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[CH;+0:4]-[*:5].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[CH;+0:9]-[CH2;+0:10]-[C;H0;+0:11](-[*:12])=[CH;+0:13]-1 |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3. | Wallwey C, Matuschek M, Xie XL, Li SM | 2010 Aug 7 | 20526482 |
| An old yellow enzyme gene controls the branch point between Aspergillus fumigatus and Claviceps purpurea ergot alkaloid pathways. | Coyle CM, Cheng JZ, O'Connor SE, Panaccione DG | 2010 Jun | 20435769 |
| A role for Old Yellow Enzyme in ergot alkaloid biosynthesis. | Cheng JZ, Coyle CM, Panaccione DG, O'Connor SE | 2010 Feb 17 | 20102147 |