Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.3 Acting on the CH-CH group of donors
            1.3.1 With NAD+ or NADP+ as acceptor
ID:1.3.1.103
Description:2-haloacrylate reductase.
Cath: 3.40.50.720; 3.90.180.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.3.1.103
BRENDA Enzyme Link: BRENDA 1.3.1.103
KEGG Enzyme Link: KEGG1.3.1.103
BioCyc Enzyme Link: BioCyc 1.3.1.103
ExPASy Enzyme Link: ExPASy1.3.1.103
EC2PDB Enzyme Link: EC2PDB 1.3.1.103
ExplorEnz Enzyme Link: ExplorEnz 1.3.1.103
PRIAM enzyme-specific profiles Link: PRIAM 1.3.1.103
IntEnz Enzyme Link: IntEnz 1.3.1.103
MEDLINE Enzyme Link: MEDLINE 1.3.1.103
MSA:

1.3.1.103;

Phylogenetic Tree:

1.3.1.103;

Uniprot:
M-CSA:
RHEA:36591 (S)-2-chloropropanoate + NADP(+) = 2-chloroacrylate + H(+) + NADPH
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH3;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[CH2;+0:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds.Kurata A, Kurihara T, Kamachi H, Esaki N2005 May 2715781461