| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.106 |
|---|---|
| Description: | Cobalt-precorrin-6A reductase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.3.1.106 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.106 |
| KEGG Enzyme Link: | KEGG1.3.1.106 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.106 |
| ExPASy Enzyme Link: | ExPASy1.3.1.106 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.106 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.106 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.106 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.106 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.106 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15625 | Co-precorrin-6B + NAD(+) = Co-precorrin-6A + H(+) + NADH |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[CH;+0:4](-[*:5])-[*:6].[*:7]-[c;H0;+0:8]1:[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:[n+;H0:12](-[*:13]):[cH;+0:14]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[C;H0;+0:4](-[*:5])-[*:6].[*:7]-[C;H0;+0:8]1=[CH;+0:14]-[N;H0;+0:12](-[*:13])-[CH;+0:11]=[CH;+0:10]-[CH2;+0:9]-1 |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12). | Moore SJ, Lawrence AD, Biedendieck R, Deery E, Frank S, Howard MJ, Rigby SE, Warren MJ | 2013 Sep 10 | 23922391 |
| Role of the precorrin 6-X reductase gene in cobamide biosynthesis in Methanococcus maripaludis. | Kim W, Major TA, Whitman WB | 2005 Dec | 16243778 |