EC number:1.3.1.109
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.109 |
|---|---|
| Description: | Butanoyl-CoA dehydrogenase (NAD(+),ferredoxin). |
| Alternative Name: |
Butanoyl-CoA dehydrogenase/Etf complex. Bifurcating butanoyl-CoA dehydrogenase. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.109 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.109 |
| KEGG Enzyme Link: | KEGG1.3.1.109 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.109 |
| ExPASy Enzyme Link: | ExPASy1.3.1.109 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.109 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.109 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.109 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.109 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.109 |
EC number:1.3.1.109
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46960 | butanoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (2E)-butenoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[Fe;H0;+0:6]-[*:7].[*:8]-[Fe;H0;+0:9]-[*:10].[*:11]-[c;H0;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[n+;H0:16](-[*:17]):[cH;+0:18]:1.[*:19]-[n+;H0:20]1:[cH;+0:21]:[cH;+0:22]:[cH;+0:23]:[c;H0;+0:24](-[*:25]):[cH;+0:26]:1>>[*:11]-[C;H0;+0:12]1=[CH;+0:18]-[N;H0;+0:16](-[*:17])-[CH;+0:15]=[CH;+0:14]-[CH2;+0:13]-1.[*:1]-[CH;+0:2]=[CH;+0:3]-[*:4].[*:5]-[Fe+;H0:6]-[*:7].[*:8]-[Fe+;H0:9]-[*:10].[*:19]-[N;H0;+0:20]1-[CH;+0:21]=[CH;+0:22]-[CH2;+0:23]-[C;H0;+0:24](-[*:25])=[CH;+0:26]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Studies on the mechanism of electron bifurcation catalyzed by electron transferring flavoprotein (Etf) and butyryl-CoA dehydrogenase (Bcd) of Acidaminococcus fermentans. | Chowdhury NP, Mowafy AM, Demmer JK, Upadhyay V, Koelzer S, Jayamani E, Kahnt J, Hornung M, Demmer U, Ermler U, Buckel W | 2014 Feb 21 | 24379410 |
| Effect of an oxygen-tolerant bifurcating butyryl coenzyme A dehydrogenase/electron-transferring flavoprotein complex from Clostridium difficile on butyrate production in Escherichia coli. | Aboulnaga el-H, Pinkenburg O, Schiffels J, El-Refai A, Buckel W, Selmer T | 2013 Aug | 23772070 |
| Coupled ferredoxin and crotonyl coenzyme A (CoA) reduction with NADH catalyzed by the butyryl-CoA dehydrogenase/Etf complex from Clostridium kluyveri. | Li F, Hinderberger J, Seedorf H, Zhang J, Buckel W, Thauer RK | 2008 Feb | 17993531 |