EC number:1.3.1.110
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.3 Acting on the CH-CH group of donors |
| 1.3.1 With NAD+ or NADP+ as acceptor |
| ID: | 1.3.1.110 |
|---|---|
| Description: | Lactate dehydrogenase (NAD(+),ferredoxin). |
| Alternative Name: |
Electron bifurcating LDH/Etf complex. |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.3.1.110 |
| BRENDA Enzyme Link: | BRENDA 1.3.1.110 |
| KEGG Enzyme Link: | KEGG1.3.1.110 |
| BioCyc Enzyme Link: | BioCyc 1.3.1.110 |
| ExPASy Enzyme Link: | ExPASy1.3.1.110 |
| EC2PDB Enzyme Link: | EC2PDB 1.3.1.110 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.3.1.110 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.3.1.110 |
| IntEnz Enzyme Link: | IntEnz 1.3.1.110 |
| MEDLINE Enzyme Link: | MEDLINE 1.3.1.110 |
EC number:1.3.1.110
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:46964 | lactate + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[OH;+0:4].[*:5]-[Fe;H0;+0:6]-[*:7].[*:8]-[Fe;H0;+0:9]-[*:10].[*:11]-[c;H0;+0:12]1:[cH;+0:13]:[cH;+0:14]:[cH;+0:15]:[n+;H0:16](-[*:17]):[cH;+0:18]:1.[*:19]-[n+;H0:20]1:[cH;+0:21]:[cH;+0:22]:[cH;+0:23]:[c;H0;+0:24](-[*:25]):[cH;+0:26]:1>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:11]-[C;H0;+0:12]1=[CH;+0:18]-[N;H0;+0:16](-[*:17])-[CH;+0:15]=[CH;+0:14]-[CH2;+0:13]-1.[*:5]-[Fe+;H0:6]-[*:7].[*:8]-[Fe+;H0:9]-[*:10].[*:19]-[N;H0;+0:20]1-[CH;+0:21]=[CH;+0:22]-[CH2;+0:23]-[C;H0;+0:24](-[*:25])=[CH;+0:26]-1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel mode of lactate metabolism in strictly anaerobic bacteria. | Weghoff MC, Bertsch J, Müller V | 2015 Mar | 24762045 |